1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]ethanone

Base Information

Chemical Name:1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]ethanone
CAS No.:30403-01-1
Molecular Formula:C14H18 O4
Molecular Weight:250.295
Hs Code.:
Mol file:30403-01-1.mol

Synonyms:Acetophenone,2',4'-dihydroxy-6'-methoxy-3'-(3-methyl-2-butenyl)- (6CI,8CI); Ethanone, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-(9CI); Preremirol

Suppliers and Price of 1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]ethanone

Chemical Property:

Melting Point:169-170 °C
Boiling Point:403.5±35.0 °C(Predicted)
PKA:8.15±0.28(Predicted)
PSA：66.76000
Density:1.150±0.06 g/cm3(Predicted)
LogP:2.81770

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]ethanone

There total 9 articles about 1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 450336-14-8
1-(2-hydroxy-6-methoxy-4-(methoxymethoxy)-3-(3-methylbut-2-enyl)phenyl)ethanone

: 30403-01-1
1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]ethanone

Guidance literature:: With hydrogenchloride; In methanol; for 0.25h; Heating;
DOI:10.1081/SCC-120003156

Reference yield: 73.0%

: 2',4'-dimethoxymethyloxy-6'-methoxy-3'-(3-methylbut-2-en-1-yloxy)acetophenone

: 30403-01-1
1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]ethanone

Guidance literature:: With hydrogenchloride; water; In methanol; for 0.666667h; Reflux; Inert atmosphere;
DOI:10.1021/acs.jnatprod.6b00646

Reference yield:

: 65490-09-7
2'-hydroxy-4',6'-bis(methoxymethoxy)acetophenone

: 30403-01-1
1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]ethanone

Guidance literature:: Multi-step reaction with 4 steps

1.1: K₂CO₃ / acetone / 4 h / Heating

1.2: 91 percent / SiO₂ / flash column chromatography

2.1: 90 percent / N,N-dimethylaniline / 4.5 h / Heating

3.1: 86 percent / K₂CO₃ / acetone / 0.5 h / Heating

4.1: 88 percent / 3N HCl / methanol / 0.25 h / Heating

With hydrogenchloride; potassium carbonate; N,N-dimethyl-aniline; In methanol; acetone; 2.1: Claisen rearrangement;
DOI:10.1081/SCC-120003156