Benzeneacetic acid, 3-(diethylamino)-2,3-dioxopropyl ester

Base Information

Chemical Name:Benzeneacetic acid, 3-(diethylamino)-2,3-dioxopropyl ester
CAS No.:497872-20-5
Molecular Formula:C15H19NO4
Molecular Weight:277.32
Hs Code.:
DSSTox Substance ID:DTXSID40479852
Nikkaji Number:J1.866.437B

Synonyms:497872-20-5;Benzeneacetic acid, 3-(diethylamino)-2,3-dioxopropyl ester;DTXSID40479852

Suppliers and Price of Benzeneacetic acid, 3-(diethylamino)-2,3-dioxopropyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzeneacetic acid, 3-(diethylamino)-2,3-dioxopropyl ester

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:277.13140809
Heavy Atom Count:20
Complexity:344

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(=O)C(=O)COC(=O)CC1=CC=CC=C1

Technology Process of Benzeneacetic acid, 3-(diethylamino)-2,3-dioxopropyl ester

There total 4 articles about Benzeneacetic acid, 3-(diethylamino)-2,3-dioxopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 855526-49-7
phenylacetic acid 3-(diethylamino)-2-hydroxy-3-oxopropyl ester

: 497872-20-5
phenylacetic acid 3-(diethylamino)-2,3-dioxopropyl ester

Guidance literature:: With pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1021/jo050246s

Reference yield:

: 103-80-0
phenylacetyl chloride

: 497872-20-5
phenylacetic acid 3-(diethylamino)-2,3-dioxopropyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / pyridine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 24 h / 20 °C

2: 68 percent / PCC / CH₂Cl₂ / 24 h / 20 °C

With pyridine; dmap; pyridinium chlorochromate; In dichloromethane;
DOI:10.1021/jo050246s

Reference yield:

: 477211-58-8
N,N-diethyl-2,3-dihydroxypropanamide

: 497872-20-5
phenylacetic acid 3-(diethylamino)-2,3-dioxopropyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / pyridine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 24 h / 20 °C

2: 68 percent / PCC / CH₂Cl₂ / 24 h / 20 °C

With pyridine; dmap; pyridinium chlorochromate; In dichloromethane;
DOI:10.1021/jo050246s