(3-methyloxiran-2-yl)methanol

Base Information

• Chemical Name: (3-methyloxiran-2-yl)methanol
• CAS No.: 872-38-8
• Molecular Formula: C4H8 O2
• Molecular Weight: 88.1063
• Mol file: 872-38-8.mol

Synonyms:1-Butanol,2,3-epoxy- (6CI,7CI,8CI); Oxiranemethanol, 3-methyl-(9CI); 2,3-Epoxy-1-butanol; 2,3-Epoxybutanol; 3-Methyloxiranemethanol; NSC 34457

Chemical Property of (3-methyloxiran-2-yl)methanol

Chemical Property:

• Vapor Pressure: 1.06mmHg at 25°C
• Boiling Point: 156.2°Cat760mmHg
• Flash Point: 69.9°C
• Density: 1.063g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3-methyloxiran-2-yl)methanol

There total 8 articles about (3-methyloxiran-2-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(E)-but-2-enol (504-61-0,542-72-3) → 2,3-epoxybutan-1-ol (872-38-8,26097-34-7)

Guidance literature:

With tetrabutylphosphonium peroxotantalate; dihydrogen peroxide; In water; at 0 ℃; for 3.5h; chemoselective reaction; Schlenk technique;

DOI:10.1002/chem.201605661

Reference yield: 95.9%

(E/Z)-2-buten-1-ol (6117-91-5,542-72-3) → 2,3-epoxybutan-1-ol (872-38-8,26097-34-7)

Guidance literature:

With C₁₆H₃₆N⁽¹⁺⁾*H₂NbO₅^(1-); dihydrogen peroxide; In water; at 0 ℃; for 6h; chemoselective reaction;

DOI:10.1021/acscatal.6b00786

Reference yield:

methanol (67-56-1) + (E/Z)-2-buten-1-ol (6117-91-5,542-72-3) → 2,3-epoxybutan-1-ol (872-38-8,26097-34-7) + butane-1,2,3-triol (4435-50-1) + 2-methoxy-butane-1,3-diol + 3-methoxy-butane-1,2-diol

Guidance literature:

With dihydrogen peroxide; titanium silicate; at 50 ℃; Further Variations:; various reaction time; Product distribution;

DOI:10.1039/b002055i

upstream raw materials:

(E/Z)-2-buten-1-ol

epoxybutene

(E)-but-2-enol

cis-2-buten-1-ol

Downstream raw materials:

3-methyl-5H-furan-2-one

butane-1,2,3-triol

2-phenylbutane-1,3-diol

Refernces

• 1、 Dai, Sheng,Ding, Bingjie,Gong, Xueqing,Hou, Zhenshan,Li, Difan,Tang, Xuan,Xu, Beibei,Yao, Yefeng,Zhang, Tong,Zheng, Anna,Zhou, Qingqing. "Role of Organic Fluoride Salts in Stabilizing Niobium Oxo-Clusters Catalyzing Epoxidation". . p. 8190 - 8203. Retrieved 2021/07/26.
• 2、 Zhou, Qingqing,Ye, Man,Ma, Wenbao,Li, Difan,Ding, Bingjie,Chen, Manyu,Yao, Yefeng,Gong, Xueqing,Hou, Zhenshan. "Ionic Liquid Stabilized Niobium Oxoclusters Catalyzing Oxidation of Sulfides with Exceptional Activity". . p. 4206 - 4217. Retrieved 2019/03/26.