[(2S,3S)-3-(4-fluorophenyl)oxiran-2-yl]-phenylmethanone

Base Information

Chemical Name:[(2S,3S)-3-(4-fluorophenyl)oxiran-2-yl]-phenylmethanone
CAS No.:27729-98-2
Molecular Formula:C₁₅H₁₁FO₂
Molecular Weight:242.25
Hs Code.:
DSSTox Substance ID:DTXSID50182082
Nikkaji Number:J417.720G
Wikidata:Q83052745
Mol file:27729-98-2.mol

Synonyms:Methanone, (3-(4-fluorophenyl)oxiranyl)phenyl-, trans-;27729-98-2;CCRIS 2226;[(2S,3S)-3-(4-fluorophenyl)oxiran-2-yl]-phenylmethanone;DTXSID50182082;BRN 5338714;trans-(3-(4-Fluorophenyl)oxiranyl)phenylmethanone;Propiophenone, 2,3-epoxy-3-(p-fluorophenyl)-, trans-;(2S,3S)-1-Phenyl-3-(4-fluorophenyl)-2,3-epoxy-1-propanone

Suppliers and Price of [(2S,3S)-3-(4-fluorophenyl)oxiran-2-yl]-phenylmethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [(2S,3S)-3-(4-fluorophenyl)oxiran-2-yl]-phenylmethanone

Chemical Property:

Vapor Pressure:9.91E-06mmHg at 25°C
Boiling Point:372°C at 760 mmHg
Flash Point:172.7°C
Density:1.277g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:242.07430775
Heavy Atom Count:18
Complexity:304

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C2C(O2)C3=CC=C(C=C3)F
Isomeric SMILES:C1=CC=C(C=C1)C(=O)[C@@H]2[C@H](O2)C3=CC=C(C=C3)F

Technology Process of [(2S,3S)-3-(4-fluorophenyl)oxiran-2-yl]-phenylmethanone

There total 7 articles about [(2S,3S)-3-(4-fluorophenyl)oxiran-2-yl]-phenylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1608-51-1
4-fluorochalcone

: 27729-98-2,42846-54-8,137461-30-4
trans-2,3-epoxy-3-(4-fluorophenyl)-1-phenylpropan-1-one

Guidance literature:: With lithium hydroxide; dihydrogen peroxide; Merrifield resin bound DABCO chloride salt; In diethyl ether; at 20 ℃; for 28h;

Reference yield: 61.0%

: 124-38-9,18923-20-1
carbon dioxide

: 459-57-4
4-fluorobenzaldehyde

: 70-11-1
α-bromoacetophenone

: 4-(4-fluorophenyl)-5-benzoyl-1,3-dioxolan-2-one

: 27729-98-2,42846-54-8,137461-30-4
trans-2,3-epoxy-3-(4-fluorophenyl)-1-phenylpropan-1-one

Guidance literature:: With lithium diisopropyl amide; In 1,4-dioxane; at 35 ℃; for 0.166667h; under 760.051 Torr;
DOI:10.1021/jo1020294

Reference yield:

: 3-(tert-butylperoxy)-3-(4-fluorophenyl)-1-phenylpropan-1-one

: 27729-98-2,42846-54-8,137461-30-4
trans-2,3-epoxy-3-(4-fluorophenyl)-1-phenylpropan-1-one

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In 1,3,5-trimethyl-benzene; at 25 ℃; for 108.5h; Schlenk technique;
DOI:10.1021/acs.orglett.0c00295