Benzaldehyde, 2-bromo-3-methoxy-4-(phenylmethoxy)-

Base Information

Chemical Name:Benzaldehyde, 2-bromo-3-methoxy-4-(phenylmethoxy)-
CAS No.:499218-04-1
Molecular Formula:C15H13BrO3
Molecular Weight:321.17
Hs Code.:
DSSTox Substance ID:DTXSID00465236
Nikkaji Number:J2.818.646K
Wikidata:Q82291039

Synonyms:499218-04-1;Benzaldehyde, 2-bromo-3-methoxy-4-(phenylmethoxy)-;SCHEMBL3543787;DTXSID00465236

Suppliers and Price of Benzaldehyde, 2-bromo-3-methoxy-4-(phenylmethoxy)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Benzaldehyde, 2-bromo-3-methoxy-4-(phenylmethoxy)-

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:320.00481
Heavy Atom Count:19
Complexity:279

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1Br)C=O)OCC2=CC=CC=C2

Technology Process of Benzaldehyde, 2-bromo-3-methoxy-4-(phenylmethoxy)-

There total 4 articles about Benzaldehyde, 2-bromo-3-methoxy-4-(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 89984-24-7
2-bromo-4-hydroxy-3-methoxy-benzaldehyde

: 100-39-0
benzyl bromide

: 499218-04-1
4-(benzyloxy)-2-bromo-3-methoxybenzaldehyde

Guidance literature:: With potassium carbonate; sodium iodide; In N,N-dimethyl-formamide; Reflux;

Reference yield: 89.0%

: 89984-24-7
2-bromo-4-hydroxy-3-methoxy-benzaldehyde

: 100-44-7
benzyl chloride

: 499218-04-1
4-(benzyloxy)-2-bromo-3-methoxybenzaldehyde

Guidance literature:: With potassium carbonate; sodium iodide; In methanol; for 6h; Heating;
DOI:10.1021/ol035506b

Reference yield:

: 89984-23-6
2-amino-4-hydroxy-3-methoxy-benzaldehyde

: 499218-04-1
4-(benzyloxy)-2-bromo-3-methoxybenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: HBr; sodium nitrite / H₂O / 0.75 h / 0 - 5 °C

1.2: 88 percent / CuBr / H₂O / 1 h / 70 °C

2.1: 89 percent / potassium carbonate; sodium iodide / methanol / 4 h / Heating

With hydrogen bromide; potassium carbonate; sodium iodide; sodium nitrite; In methanol; water;
DOI:10.1021/jo052589w