6-Chloro-3-(2-cyclopropyl-6-methylphenoxy)pyridazin-4-ol

Base Information

Chemical Name:6-Chloro-3-(2-cyclopropyl-6-methylphenoxy)pyridazin-4-ol
CAS No.:499223-49-3
Molecular Formula:C14H13ClN2O2
Molecular Weight:276.722
Hs Code.:
European Community (EC) Number:807-135-1
DSSTox Substance ID:DTXSID80468048
Wikidata:Q82295144

Synonyms:499223-49-3;6-chloro-3-(2-cyclopropyl-6-methylphenoxy)pyridazin-4-ol;6-chloro-3-(2-cyclo-propyl-6-methylphenoxy)-4-pyridazinol;6-chloro-3-(2-cyclopropyl-6-methylphenoxy)-4-pyridazinol;SCHEMBL121823;SCHEMBL20482023;DTXSID80468048;GZJVZGUUTYWVTP-UHFFFAOYSA-N;MFCD30557605;SY320818;F86801;6-chloro-3-(2-cyclopropyl-6-methyl-phenoxy)-4-pyridazinol

Suppliers and Price of 6-Chloro-3-(2-cyclopropyl-6-methylphenoxy)pyridazin-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-Chloro-3-(2-cyclopropyl-6-methylphenoxy)pyridazin-4-ol

Chemical Property:

PSA：55.24000
LogP:3.81370
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:276.0665554
Heavy Atom Count:19
Complexity:443

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=CC=C1)C2CC2)OC3=NNC(=CC3=O)Cl

Technology Process of 6-Chloro-3-(2-cyclopropyl-6-methylphenoxy)pyridazin-4-ol

There total 3 articles about 6-Chloro-3-(2-cyclopropyl-6-methylphenoxy)pyridazin-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.1%

: 2779-81-9
3,6-dichloropyridazin-4-ol

: 1283713-01-8
sodium 2-cyclopropyl-6-methylphenoxide

: 499223-49-3
6-chloro-3-(2-cyclopropyl-6-methylphenoxy)-4-pyridazinol

Guidance literature:: 3,6-dichloropyridazin-4-ol; sodium 2-cyclopropyl-6-methylphenoxide; In toluene; tert-butyl alcohol; at 20 - 140 ℃; for 3h; Autoclave;

With water; In toluene; for 0.5h; Product distribution / selectivity;

Reference yield: 81.1%

: 499235-44-8
4,6-Dichloro-3-(2-cyclopropyl-6-methylphenoxy)pyridazine

: 499223-49-3
6-chloro-3-(2-cyclopropyl-6-methylphenoxy)-4-pyridazinol

Guidance literature:: With sodium hydroxide; In water; dimethyl sulfoxide; at 20 ℃; for 96h;

Reference yield:

: 499236-68-9
2-cyclopropyl-6-methylphenol

: 2779-81-9
3,6-dichloropyridazin-4-ol

: 499223-49-3
6-chloro-3-(2-cyclopropyl-6-methylphenoxy)-4-pyridazinol

Guidance literature:: 2-cyclopropyl-6-methylphenol; With sodium hydroxide; In 1,2-dichloro-benzene; at 20 - 180 ℃; for 0.5h;

3,6-dichloropyridazin-4-ol; In 1,2-dichloro-benzene; tert-butyl alcohol; at 180 ℃; for 7h;

With hydrogenchloride; In water; 1,2-dichloro-benzene; toluene; at 0 - 20 ℃; for 1h; Product distribution / selectivity;