3-BroMo-1-(diMethylsulfaMoyl)pyrazole

Base Information

• Chemical Name: 3-BroMo-1-(diMethylsulfaMoyl)pyrazole
• CAS No.: 500011-84-7
• Molecular Formula: C5H8BrN3O2S
• Molecular Weight: 254.10500
• Hs Code.: 2935009090
• Mol file: 500011-84-7.mol

Synonyms:3-bromo-N,N-dimethyl-1H-pyrazole-1-sulfonamide;bromure de bromo-3 propyltriphenylphosphonium;3-bromo-pyrazole-1-sulfonic acid dimethylamide;

Chemical Property of 3-BroMo-1-(diMethylsulfaMoyl)pyrazole

Chemical Property:

• Boiling Point: 345.5±34.0 °C(Predicted)
• PKA: -4.94±0.12(Predicted)
• PSA: 63.58000
• Density: 1.79±0.1 g/cm3(Predicted)
• LogP: 1.38090
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

3-Bromo-1-(dimethylsulfamoyl)pyrazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-Bromo-1-(dimethylsulfamoyl)pyrazole is used as a reactant in the preparation of pyrazolopyridines as tyrosine kinase 2 inhibitors for treatment of autoimmune diseases.

Technology Process of 3-BroMo-1-(diMethylsulfaMoyl)pyrazole

There total 1 articles about 3-BroMo-1-(diMethylsulfaMoyl)pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-dimethyl-1H-pyrazole-1-sulfonamide (133228-21-4) → 3-bromo-N,N-dimethyl-1H-pyrazole-1-sulfonamide (500011-84-7)

Guidance literature:

N,N-dimethyl-1H-pyrazole-1-sulfonamide; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - -60 ℃; for 0.25h;

With 1,2-dibromo-1,1,2,2-tetrachloroethane; In tetrahydrofuran; hexane; at -70 ℃; for 0.25h;

Reference yield:

3-bromo-N,N-dimethyl-1H-pyrazole-1-sulfonamide (500011-84-7) → 3-bromo-1H-pyrazole (14521-80-3,1174132-74-1)

Guidance literature:

With trifluoroacetic acid; at 20 ℃; for 0.5h;

upstream raw materials:

N,N-dimethyl-1H-pyrazole-1-sulfonamide

Downstream raw materials:

3-bromo-1H-pyrazole