2,4-Pentadienoyl chloride,5-(1,3-benzodioxol- 5-yl)-

Base Information

• Chemical Name: 2,4-Pentadienoyl chloride,5-(1,3-benzodioxol- 5-yl)-
• CAS No.: 4711-72-2
• Molecular Formula: C12H9ClO3
• Molecular Weight: 236.655
• Mol file: 4711-72-2.mol

Synonyms:5-Benzo[1,3]dioxol-5-yl-penta-2,4-dienoylchlorid;5-benzo[1,3]dioxol-5-yl-penta-2,4-dienoyl chloride;5t-Benzo[1,3]dioxol-5-yl-penta-2t,4-dienoylchlorid;SCT-08;(2E,4E)-5-Benzo[1,3]dioxol-5-yl-penta-2,4-dienoyl chloride;Piperinsaeure-chlorid;5t-benzo[1,3]dioxol-5-yl-penta-2t,4-dienoyl chloride;

Chemical Property of 2,4-Pentadienoyl chloride,5-(1,3-benzodioxol- 5-yl)-

Chemical Property:

• PSA: 35.53000
• LogP: 2.75010

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-Pentadienoyl chloride,5-(1,3-benzodioxol- 5-yl)-

There total 1 articles about 2,4-Pentadienoyl chloride,5-(1,3-benzodioxol- 5-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienoate (6190-46-1,89812-63-5) → piperic acid chloride (4711-72-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) alkali, 2) acid

2: oxalyl chloride / benzene

With oxalyl dichloride; In benzene;

Reference yield: 89.0%

cyclohexylamine (108-91-8,157973-60-9) + piperic acid chloride (4711-72-2) → (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-N-cyclohexylpenta-2,4-dienamide (263744-11-2)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 60 ℃;

DOI:10.1002/(SICI)1526-4998(200002)56:2<168::AID-PS110>3.0.CO;2-H

Reference yield: 86.0%

isobutylamine (78-81-9) + piperic acid chloride (4711-72-2) → piperlonguminine (5950-12-9)

Guidance literature:

With triethylamine; at 20 ℃; for 5h; Cooling with ice;

DOI:10.1248/cpb.c14-00874

upstream raw materials:

methyl (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienoate

Downstream raw materials:

Piperine

piperlonguminine

(2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-N-cyclohexylpenta-2,4-dienamide

(2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-1-morpholinopenta-2,4-dien-1-one

Refernces