4-Chloro-2-[1-(3,4-dimethylanilino)ethyl]phenol

Base Information

Chemical Name:4-Chloro-2-[1-(3,4-dimethylanilino)ethyl]phenol
CAS No.:6430-25-7
Molecular Formula:C20H18 Ge O
Molecular Weight:346.952
Hs Code.:
DSSTox Substance ID:DTXSID30410653

Synonyms:4-chloro-2-[1-(3,4-dimethylanilino)ethyl]phenol;6430-25-7;DTXSID30410653;AE-848/42278667

Suppliers and Price of 4-Chloro-2-[1-(3,4-dimethylanilino)ethyl]phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-Chloro-2-[1-(3,4-dimethylanilino)ethyl]phenol

Chemical Property:

Vapor Pressure:2.18E-07mmHg at 25°C
Boiling Point:412.4°Cat760mmHg
Flash Point:203.2°C
Density:1.2g/cm³
XLogP3:4.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:275.1076919
Heavy Atom Count:19
Complexity:286

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=C(C=C1)NC(C)C2=C(C=CC(=C2)Cl)O)C

Technology Process of 4-Chloro-2-[1-(3,4-dimethylanilino)ethyl]phenol

There total 2 articles about 4-Chloro-2-[1-(3,4-dimethylanilino)ethyl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 3839-32-5
triphenylgermyl lithium

: 141-78-6
ethyl acetate

: 6430-25-7
acetyl-triphenylgermane

Guidance literature:: In tetrahydrofuran; byproducts: LiOC2H5, Ge(C6H5)3H; dropwise addn. of organic compd. (via syringe) to a soln. of Li-compd. (prepd. from GePh3 and BuLi in hexane) at room temp. under Ar, stirred for 10 min; quenched with aq. NH4Cl, organic layer extd. (ether), dried over MgSO4, evapd., flash chromy.;
DOI:10.1246/cl.1985.1829

Reference yield:

: 6430-25-7
acetyl-triphenylgermane

Guidance literature:: a) Triphenylgermyllithium, Acetylchlorid;
DOI:10.1016/S0022-328X(00)92649-4

Reference yield: 74.0%

: 6430-25-7
acetyl-triphenylgermane

: 67-72-1
hexachloroethane

: 918-00-3,861255-82-5
1,1,1-trichloroacetone

: 1626-24-0
chlorotriphenylgermane

: 75-36-5
acetyl chloride

Guidance literature:: With tetrachloromethane; In tetrachloromethane; Irradiation (UV/VIS); Ph3GeCOMe photolyzed in CCl4;
DOI:10.1016/0022-328X(86)84028-1