Technology Process of 5-[3-(4-Methoxyphenyl)propyl]-2H-1,3-benzodioxole
There total 4 articles about 5-[3-(4-Methoxyphenyl)propyl]-2H-1,3-benzodioxole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
5%-palladium/activated carbon; hydrogen;
In
methanol; ethyl acetate;
at 20 ℃;
for 6h;
DOI:10.1016/j.tet.2020.131494
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
methanol; ethyl acetate;
at 20 ℃;
for 16h;
DOI:10.1016/j.tetlet.2020.152756
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 - 0 °C
1.2: 19 h / -78 - 20 °C
2.1: hydrogen; palladium 10% on activated carbon / ethyl acetate; methanol / 16 h / 20 °C
With
palladium 10% on activated carbon; hydrogen; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol; ethyl acetate;
DOI:10.1016/j.tetlet.2020.152756
