2-Fluoro-6-phenylpyridine-3-carboxylic acid

Base Information

Chemical Name:2-Fluoro-6-phenylpyridine-3-carboxylic acid
CAS No.:505083-01-2
Molecular Formula:C12H8FNO2
Molecular Weight:217.199
Hs Code.:2933399090
Mol file:505083-01-2.mol

Synonyms:2-Fluoro-6-phenylnicotinic acid;QC-8316;2-fluoro-6-phenyl-pyridine-3-carboxylic acid;

Suppliers and Price of 2-Fluoro-6-phenylpyridine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Fluoro-6-phenylnicotinicacid 95+%
1g
$ 535.00

Chemenu
2-fluoro-6-phenylnicotinicacid 95%
1g
$ 505.00

American Custom Chemicals Corporation
2-FLUORO-6-PHENYLPYRIDINE-3-CARBOXYLIC ACID 95.00%
5MG
$ 498.49

Alichem
2-Fluoro-6-phenyl-3-pyridinecarboxylicacid
1g
$ 1848.00

Alichem
2-Fluoro-6-phenyl-3-pyridinecarboxylicacid
500mg
$ 1029.00

Alichem
2-Fluoro-6-phenyl-3-pyridinecarboxylicacid
250mg
$ 652.80

Total 8 raw suppliers

Chemical Property of 2-Fluoro-6-phenylpyridine-3-carboxylic acid

Chemical Property:

Vapor Pressure:8.42E-07mmHg at 25°C
Boiling Point:390.6oC at 760 mmHg
Flash Point:190oC
PSA：50.19000
Density:1.318g/cm3
LogP:2.58590
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-Fluoro-6-phenylnicotinicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Fluoro-6-phenylpyridine-3-carboxylic acid

There total 2 articles about 2-Fluoro-6-phenylpyridine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 180606-17-1
2-fluoro-6-phenyl-pyridine

: 124-38-9,18923-20-1
carbon dioxide

: 505083-01-2
2-fluoro-6-phenyl-pyridine-3-carboxylic acid

Guidance literature:: 2-fluoro-6-phenyl-pyridine; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.5h;

carbon dioxide; In tetrahydrofuran; for 0.166667h;

Reference yield:

: 1513-65-1
2,6-difluoro pyridine

: 591-51-5
phenyllithium

: 505083-01-2
2-fluoro-6-phenyl-pyridine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrahydrofuran; hexane / 0.5 h / -40 °C

2.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C

2.2: 0.17 h / -78 °C

With lithium diisopropyl amide; In tetrahydrofuran; hexane;