N-acetyl-N-(2-oxopropyl)acetamide

Base Information

• Chemical Name: N-acetyl-N-(2-oxopropyl)acetamide
• CAS No.: 51862-97-6
• Molecular Formula: C7H11NO3
• Molecular Weight: 157.169
• Hs Code.: 2925190090
• DSSTox Substance ID: DTXSID60483491
• Nikkaji Number: J1.150.814F
• Wikidata: Q82320857
• Mol file: 51862-97-6.mol

Synonyms:N-acetyl-N-(2-oxopropyl)acetamide;51862-97-6;N-Acetyl-N-(2-oxo-propyl)-acetamide;N,N-diacetylaminoacetone;SCHEMBL2140134;DTXSID60483491;MFCD00015628;SC3701;AKOS005175017;SB37469;AS-54655;CS-0200056;A871143

Chemical Property of N-acetyl-N-(2-oxopropyl)acetamide

Chemical Property:

• PSA: 54.45000
• LogP: -0.02960
• Storage Temp.: 2-8°C
• XLogP3: -0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 157.07389321
• Heavy Atom Count: 11
• Complexity: 184

Purity/Quality:

97% ^*data from raw suppliers

N-acetyl-N-(2-oxopropyl)acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)CN(C(=O)C)C(=O)C

Technology Process of N-acetyl-N-(2-oxopropyl)acetamide

There total 2 articles about N-acetyl-N-(2-oxopropyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

→ diacetylamino-acetone (51862-97-6)

Guidance literature:

Reference yield: 48.0%

acetic anhydride (108-24-7) + glycine (56-40-6,18875-39-3,25718-94-9) → diacetylamino-acetone (51862-97-6)

Guidance literature:

With pyridine; at 20 ℃; for 20h; Reflux;

DOI:10.1002/psc.2873

Reference yield: 68.0%

diacetylamino-acetone (51862-97-6) + semicarbazide hydrochloride (563-41-7) → aminoacetone-semicarbazone hydrochloride (10469-70-2)

Guidance literature:

diacetylamino-acetone; With hydrogenchloride; In water; at 20 ℃; for 20h; Reflux;

semicarbazide hydrochloride; In water; for 2h;

DOI:10.1002/psc.2873

upstream raw materials:

acetic anhydride

glycine

Downstream raw materials:

2,3-dihydro-4H-1-benzopyran-4-one

2,5-dimethyloxazole

aminoacetone-semicarbazone hydrochloride