1-(3-Bromophenyl)-3-(dimethylamino)propan-1-one

Base Information

Chemical Name:1-(3-Bromophenyl)-3-(dimethylamino)propan-1-one
CAS No.:51949-05-4
Molecular Formula:C11H14BrNO
Molecular Weight:256.142
Hs Code.:
DSSTox Substance ID:DTXSID70358368
Wikidata:Q82138881
ChEMBL ID:CHEMBL1625206
Mol file:51949-05-4.mol

Synonyms:1-(3-bromophenyl)-3-(dimethylamino)propan-1-one;51949-05-4;STK093370;Oprea1_242159;SCHEMBL3870786;CHEMBL1625206;DTXSID70358368;AKOS005264566;EN300-8557198

Suppliers and Price of 1-(3-Bromophenyl)-3-(dimethylamino)propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(3-Bromophenyl)-3-(dimethylamino)propan-1-one

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:255.02588
Heavy Atom Count:14
Complexity:194

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCC(=O)C1=CC(=CC=C1)Br

Technology Process of 1-(3-Bromophenyl)-3-(dimethylamino)propan-1-one

There total 2 articles about 1-(3-Bromophenyl)-3-(dimethylamino)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 506-59-2
N,N-dimethylammonium chloride

: 2142-63-4
1-(3-Bromophenyl)ethanone

: 51949-05-4
1-(3-bromophenyl)-3-(N,N-dimethylamino)-1-propanone

Guidance literature:: hydrogenchloride; In ethanol; water; Heating / reflux;

Reference yield: 62.2%

: 51949-05-4
1-(3-bromophenyl)-3-(N,N-dimethylamino)-1-propanone

Guidance literature:: With hydrogenchloride; In ethanol; water; at 80 - 90 ℃; for 16h; Inert atmosphere;

Reference yield: 35.3%

: 1346998-16-0
6-bromo-2-methoxy-3-(4-chlorobenzyl)naphthalene

: 51949-05-4
1-(3-bromophenyl)-3-(N,N-dimethylamino)-1-propanone

: 1-(7-bromo-3-methoxynaphthalen-2-yl)-2-(3-bromophenyl)-1-(4-chlorophenyl)-4-(dimethylamino) butan-2-ol

: 1-(7-bromo-3-methoxynaphthalen-2-yl)-2-(3-bromophenyl)-1-(4-chlorophenyl)-4-(dimethylamino) butan-2-ol

Guidance literature:: 6-bromo-2-methoxy-3-(4-chlorobenzyl)naphthalene; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.666667h; Inert atmosphere;

1-(3-bromophenyl)-3-(N,N-dimethylamino)-1-propanone; In tetrahydrofuran; hexane; at -78 ℃; for 10h; Inert atmosphere;

With ammonium chloride; In tetrahydrofuran; hexane; water; at -40 ℃; Inert atmosphere;
DOI:10.1016/j.bioorg.2020.104054