5-Chloro-3-methyl-3-phenyl-1,3-dihydro-2H-indol-2-one

Base Information

Chemical Name:5-Chloro-3-methyl-3-phenyl-1,3-dihydro-2H-indol-2-one
CAS No.:52181-34-7
Molecular Formula:C15H12ClNO
Molecular Weight:257.719
Hs Code.:
DSSTox Substance ID:DTXSID90603923
Nikkaji Number:J2.417.612F
Mol file:52181-34-7.mol

Synonyms:52181-34-7;SCHEMBL10826521;5-Chloro-3-methyl-3-phenyl-1,3-dihydro-2H-indol-2-one;DTXSID90603923;KXQDIAMXFBMGMH-UHFFFAOYSA-N;3-Methyl-3-phenyl-5-chlorooxindole

Suppliers and Price of 5-Chloro-3-methyl-3-phenyl-1,3-dihydro-2H-indol-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 5-Chloro-3-methyl-3-phenyl-1,3-dihydro-2H-indol-2-one

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:257.0607417
Heavy Atom Count:18
Complexity:339

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C2=C(C=CC(=C2)Cl)NC1=O)C3=CC=CC=C3

Technology Process of 5-Chloro-3-methyl-3-phenyl-1,3-dihydro-2H-indol-2-one

There total 4 articles about 5-Chloro-3-methyl-3-phenyl-1,3-dihydro-2H-indol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 15815-97-1
5-chloro-3-phenyl-2-indolinone

: 74-88-4
methyl iodide

: 52181-34-7
5-chloro-3-methyl-3-phenyl-1,3-dihydro-indol-2-one

Guidance literature:: With potassium carbonate; In water; acetone;

Reference yield:

: C₁₅H₁₂ClN

: 52181-34-7
5-chloro-3-methyl-3-phenyl-1,3-dihydro-indol-2-one

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1016/j.tetlet.2006.11.041

Reference yield:

: 823-85-8
4-fluorophenyhydrazine hydrochloride

: 52181-34-7
5-chloro-3-methyl-3-phenyl-1,3-dihydro-indol-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 60 °C

2: mCPBA / CH₂Cl₂ / 1 h / 20 °C

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; acetic acid;
DOI:10.1016/j.tetlet.2006.11.041