4-Methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one

Base Information

Chemical Name:4-Methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one
CAS No.:52239-91-5
Molecular Formula:C11H12N2O
Molecular Weight:188.229
Hs Code.:
DSSTox Substance ID:DTXSID80552118
Mol file:52239-91-5.mol

Synonyms:52239-91-5;3(2H)-Pyridazinone, 4,5-dihydro-4-methyl-6-phenyl-;4-Methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one;4,5-dihydro-4-methyl-6-phenylpyridazin-3(2H)-one;5-methyl-3-phenyl-4,5-dihydro-1H-pyridazin-6-one;SCHEMBL1754736;DTXSID80552118;MITLKHILFHLTRV-UHFFFAOYSA-N

Suppliers and Price of 4-Methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 13 raw suppliers

Chemical Property of 4-Methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:188.094963011
Heavy Atom Count:14
Complexity:254

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1CC(=NNC1=O)C2=CC=CC=C2
Use Description 4,5-dihydro-4-methyl-6-phenyl-3(2H)-pyridazinone, a chemical compound, has applications in various fields. In the pharmaceutical industry, it serves as a valuable intermediate in the synthesis of drugs and pharmaceutical compounds, contributing to the development of medications for various medical conditions. In the field of agricultural chemistry, it plays a role in the creation of pesticides and herbicides, aiding in crop protection and pest control. Additionally, 3(2H)-Pyridazinone, 4,5-dihydro-4-methyl-6-phenyl- is employed in research laboratories as a building block for designing new molecules with potential biological activities, making it a vital tool in medicinal and chemical research. Its versatile nature and significance in drug development, agriculture, and scientific exploration highlight its importance across multiple domains.

Technology Process of 4-Methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one

There total 9 articles about 4-Methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.1%

: 1771-65-9
2-methyl-4-oxo-4-phenylbutanoic acid

: 52239-91-5
4-methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one

Guidance literature:: With hydrazine hydrate; In ethanol; at 10 - 20 ℃; Product distribution / selectivity; Reflux;

Reference yield: 25.0%

: 6-ethoxy-5-methyl-3-phenyl-1-p-tosyl-1,4,5,6-tetrahydropyridazine

: 32723-45-8
4-methyl-6-phenylpyridazine

: 52239-91-5
4-methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one

Guidance literature:: With sodium ethanolate; In ethanol; for 0.333333h; Heating;

Reference yield:

: 4100-80-5
2-methylsuccinic anhydride

: 52239-91-5
4-methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum chloride

2: hydrazine / ethanol / Heating

With aluminium trichloride; hydrazine; In ethanol;
DOI:10.1021/jm00025a004