2.2-Dimethyl-4-hydroxy-3-pentanone

Base Information

Chemical Name:2.2-Dimethyl-4-hydroxy-3-pentanone
CAS No.:52279-28-4
Molecular Formula:C7H14O2
Molecular Weight:130.18500
Hs Code.:
DSSTox Substance ID:DTXSID60457152
Mol file:52279-28-4.mol

Synonyms:2.2-Dimethyl-4-hydroxy-3-pentanone;52279-28-4;SCHEMBL7620432;DTXSID60457152;CLDPAGCOQSJLSP-UHFFFAOYSA-N;4,4-dimethyl-2-hydroxy-3-pentanone

Suppliers and Price of 2.2-Dimethyl-4-hydroxy-3-pentanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2.2-Dimethyl-4-hydroxy-3-pentanone

Chemical Property:

Boiling Point:100-101.5 °C(Press: 100 Torr)
PSA：37.30000
Density:0.9483 g/cm3
LogP:0.98240
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:130.099379685
Heavy Atom Count:9
Complexity:111

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C(=O)C(C)(C)C)O

Technology Process of 2.2-Dimethyl-4-hydroxy-3-pentanone

There total 1 articles about 2.2-Dimethyl-4-hydroxy-3-pentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-56-1
methanol

: 40955-58-6
4-chloro-2,2-dimethyl-pentan-3-one

: 590-29-4
potassium formate

: 52279-28-4
2.2-Dimethyl-4-hydroxy-3-pentanone

: 7737-47-5,97869-12-0
3-hydroxy-4,4-dimethylpentan-2-one

Guidance literature:: at 150 ℃;

Reference yield: 95.0%

: 52279-28-4
2.2-Dimethyl-4-hydroxy-3-pentanone

: 7322-88-5
(S)-acetylmandelic acid

: 112597-23-6,112597-24-7
(S)-Acetoxy-phenyl-acetic acid 1,3,3-trimethyl-2-oxo-butyl ester

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; at 25 ℃; for 12h;
DOI:10.1021/jo00239a057

Reference yield:

: 52279-28-4
2.2-Dimethyl-4-hydroxy-3-pentanone

: 86016-62-8
(5-tert-butyl-2-oxo-1,3-dioxol-4-yl)methyl (S)-3-hydroxy-α-methyltyrosinate

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) pyridine, 2.) p-toluenesulfonic acid hydrate / 1.) toluene, 20 deg C to 25 deg C, 20 h, 2.) 160 deg C, 24 h

2: 6.5 g / N-bromosuccinimide, dibenzoyl peroxide / CCl₄ / 1.5 h / Heating

3: DMF / 3 h / 20 - 25 °C

With pyridine; N-Bromosuccinimide; toluene-4-sulfonic acid; N,N-dimethyl-formamide; dibenzoyl peroxide; In tetrachloromethane;
DOI:10.1021/jm00372a002