3,3'-(1,4-Phenylene)bis(1-phenylprop-2-yn-1-one)

Base Information

Chemical Name:3,3'-(1,4-Phenylene)bis(1-phenylprop-2-yn-1-one)
CAS No.:52714-30-4
Molecular Formula:C24H14O2
Molecular Weight:334.374
Hs Code.:
DSSTox Substance ID:DTXSID60531527
Nikkaji Number:J2.138.132B
Wikidata:Q82403456
Mol file:52714-30-4.mol

Synonyms:52714-30-4;3,3'-(1,4-Phenylene)bis(1-phenylprop-2-yn-1-one);DTXSID60531527;1,4-bis(3-phenyl-3-oxo-1-propynyl)benzene

Suppliers and Price of 3,3'-(1,4-Phenylene)bis(1-phenylprop-2-yn-1-one)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 3,3'-(1,4-Phenylene)bis(1-phenylprop-2-yn-1-one)

Chemical Property:

XLogP3:5.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:334.099379685
Heavy Atom Count:26
Complexity:569

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C#CC2=CC=C(C=C2)C#CC(=O)C3=CC=CC=C3

Technology Process of 3,3'-(1,4-Phenylene)bis(1-phenylprop-2-yn-1-one)

There total 5 articles about 3,3'-(1,4-Phenylene)bis(1-phenylprop-2-yn-1-one) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.2%

: 935-14-8
1,4-diethynylbenzene

: 98-88-4
benzoyl chloride

: 52714-30-4
1,1'-(1,4-phenylene)bis(3-phenylprop-2-yn-1-one)

Guidance literature:: With copper(l) iodide; triethylamine; In toluene;
DOI:10.1007/BF00995713

Reference yield: 77.0%

: 591-50-4
iodobenzene

: 201230-82-2
carbon monoxide

: 935-14-8
1,4-diethynylbenzene

: 52714-30-4
1,1'-(1,4-phenylene)bis(3-phenylprop-2-yn-1-one)

Guidance literature:: With dibromide(1-methyl-3-(2-methylpropyl)-5-phenyl-1H-imidazol-2-ylidene)pyridine palladium(II); triethylamine; In toluene; at 120 ℃; for 18h; under 10343.2 Torr; Autoclave;
DOI:10.1002/aoc.4280

Reference yield:

: 624-38-4,1032416-46-8
para-diiodobenzene

: 52714-30-4
1,1'-(1,4-phenylene)bis(3-phenylprop-2-yn-1-one)

Guidance literature:: Multi-step reaction with 2 steps

1: bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 0.5 h / 45 °C / Schlenk technique; Inert atmosphere

2: copper(l) iodide; triethylamine hydrochloride; triethylamine / 1 h / 45 °C / Schlenk technique; Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine hydrochloride; triethylamine; In tetrahydrofuran; 1: |Kumada Cross-Coupling / 2: |Sonogashira Cross-Coupling;
DOI:10.1039/c6ob00483k