2,3-Dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylic acid methyl ester

Base Information

Chemical Name:2,3-Dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylic acid methyl ester
CAS No.:527681-12-5
Molecular Formula:C9H9NO4
Molecular Weight:195.17200
Hs Code.:
Mol file:527681-12-5.mol

Synonyms:2,3-Dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylic acid methyl ester;

Suppliers and Price of 2,3-Dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylate 95+%
1g
$ 762.00

Alichem
Methyl2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylate
1g
$ 657.20

Total 9 raw suppliers

Chemical Property of 2,3-Dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylic acid methyl ester

Chemical Property:

PSA：57.65000
LogP:0.63940

Purity/Quality:

98%Min ^*data from raw suppliers

Methyl2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,3-Dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylic acid methyl ester

There total 2 articles about 2,3-Dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 527681-11-4
methyl 4,5-dihydroxypyridine-2-carboxylate

: 106-93-4
ethylene dibromide

: 527681-12-5
methyl 2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 115 ℃; for 2h;
DOI:10.1016/j.bmc.2006.09.019

Reference yield:

: 43077-77-6
4,5-dihydroxypyridine-2-carboxylic acid

: 527681-12-5
methyl 2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / sulfuric acid / 48 h / Heating

2: 86 percent / potassium carbonate / dimethylformamide / 2 h / 115 °C

With sulfuric acid; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2006.09.019

Reference yield: 94.0%

: 527681-12-5
methyl 2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylate

: 527681-13-6
2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylic acid

Guidance literature:: methyl 2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylate; With water; sodium hydroxide; In methanol; at 100 ℃; for 3h;

With hydrogenchloride; In water; pH=5;