Benzoic acid, 4-methoxy-, 4-(chlorocarbonyl)phenyl ester

Base Information

• Chemical Name: Benzoic acid, 4-methoxy-, 4-(chlorocarbonyl)phenyl ester
• CAS No.: 52899-54-4
• Molecular Formula: C15H11ClO4
• Molecular Weight: 290.703
• Mol file: 52899-54-4.mol

Synonyms:4-[(4'-Methoxybenzoyl)oxy]benzoyl chloride;4-chloroformylphenyl-4-methoxybenzoate;Benzoic acid,4-methoxy-,4-(chlorocarbonyl)phenyl ester;

Chemical Property of Benzoic acid, 4-methoxy-, 4-(chlorocarbonyl)phenyl ester

Chemical Property:

• Boiling Point: 438.0±30.0 °C(Predicted)
• PSA: 52.60000
• Density: 1.302±0.06 g/cm3(Predicted)
• LogP: 3.29340

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid, 4-methoxy-, 4-(chlorocarbonyl)phenyl ester

There total 6 articles about Benzoic acid, 4-methoxy-, 4-(chlorocarbonyl)phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

4-(4'-methoxybenzoyloxy)benzoic acid (52899-69-1) → 4-[(4'-Methoxybenzoyl)oxy]benzoyl chloride (52899-54-4)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; Heating;

DOI:10.1080/00268948208071024

Reference yield:

4-methoxy-benzoyl chloride (100-07-2) → 4-[(4'-Methoxybenzoyl)oxy]benzoyl chloride (52899-54-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 86 percent / Et₃N / CHCl₃ / 1 h / Ambient temperature

2: 57 percent / O₂ / cobalt bromide, manganese bromide / propionic acid / 12 h / Heating

3: 83 percent / SOCl₂, DMF / Heating

With thionyl chloride; oxygen; triethylamine; N,N-dimethyl-formamide; manganese(II) bromide; cobalt(II) bromide; In chloroform; propionic acid;

DOI:10.1080/00268948208071024

Reference yield:

4-(4'-methoxybenzoyloxy)benzaldehyde (56800-26-1) → 4-[(4'-Methoxybenzoyl)oxy]benzoyl chloride (52899-54-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 57 percent / O₂ / cobalt bromide, manganese bromide / propionic acid / 12 h / Heating

2: 83 percent / SOCl₂, DMF / Heating

With thionyl chloride; oxygen; N,N-dimethyl-formamide; manganese(II) bromide; cobalt(II) bromide; In propionic acid;

DOI:10.1080/00268948208071024

upstream raw materials:

4-(4'-methoxybenzoyloxy)benzoic acid

4-(4'-methoxybenzoyloxy)benzaldehyde

4-hydroxy-benzaldehyde

4-methoxy-benzoyl chloride