4-((4-Methoxybenzoyl)oxy)benzoic acid

Base Information

• Chemical Name: 4-((4-Methoxybenzoyl)oxy)benzoic acid
• CAS No.: 52899-69-1
• Molecular Formula: C15H12O5
• Molecular Weight: 272.257
• Hs Code.: 2918990090
• DSSTox Substance ID: DTXSID10500682
• Nikkaji Number: J1.608.556A
• Wikidata: Q72489223
• Mol file: 52899-69-1.mol

Synonyms:52899-69-1;4-((4-methoxybenzoyl)oxy)benzoic acid;4-(4-Methoxybenzoyloxy)benzoic acid;4-(4-methoxybenzoyl)oxybenzoic acid;4-[(4-Methoxybenzoyl)oxy]benzoic acid;SCHEMBL11306013;DTXSID10500682;AMY24980;BCP18876;4-((4-methoxybenzoyl)oxy)benzoicacid;AKOS005359590;FT-0730639

Chemical Property of 4-((4-Methoxybenzoyl)oxy)benzoic acid

Chemical Property:

• Melting Point: 219-220℃
• PSA: 72.83000
• Density: 1.300
• LogP: 2.61260
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 272.06847348
• Heavy Atom Count: 20
• Complexity: 338

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(=O)OC2=CC=C(C=C2)C(=O)O

Technology Process of 4-((4-Methoxybenzoyl)oxy)benzoic acid

There total 10 articles about 4-((4-Methoxybenzoyl)oxy)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

4-(4'-methoxybenzoyloxy)benzaldehyde (56800-26-1) → 4-(4'-methoxybenzoyloxy)benzoic acid (52899-69-1)

Guidance literature:

With oxygen; manganese(II) bromide; cobalt(II) bromide; In propionic acid; for 12h; Heating;

DOI:10.1080/00268948208071024

Reference yield:

4-(methoxycarbonyl)phenyl 4-methoxybenzoate (50649-66-6) → 4-(4'-methoxybenzoyloxy)benzoic acid (52899-69-1)

Guidance literature:

In ethanol; water; Alkaline conditions; Reflux;

DOI:10.1080/15421406.2017.1357430

Reference yield:

4-methoxy-benzoyl chloride (100-07-2) → 4-(4'-methoxybenzoyloxy)benzoic acid (52899-69-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / Et₃N / CHCl₃ / 1 h / Ambient temperature

2: 57 percent / O₂ / cobalt bromide, manganese bromide / propionic acid / 12 h / Heating

With oxygen; triethylamine; manganese(II) bromide; cobalt(II) bromide; In chloroform; propionic acid;

DOI:10.1080/00268948208071024

upstream raw materials:

4-(4'-methoxybenzoyloxy)benzaldehyde

4-methoxy-benzoyl chloride

4-hydroxy-benzoic acid

4-hydroxy-benzaldehyde

Downstream raw materials:

4-[(4'-Methoxybenzoyl)oxy]benzoyl chloride