1-(5-Chloro-2-hydroxy-phenyl)-3-phenyl-propenone

Base Information

Chemical Name:1-(5-Chloro-2-hydroxy-phenyl)-3-phenyl-propenone
CAS No.:52923-35-0
Molecular Formula:C₁₅H₁₁ClO₂
Molecular Weight:258.704
Hs Code.:
Mol file:52923-35-0.mol

Synonyms:5'-Chlor-2'-hydroxy-chalkon;2'-hydroxy-5'-chlorochalcone;5'-chloro-2'-hydroxychalcone;2-Propen-1-one,1-(5-chloro-2-hydroxyphenyl)-3-phenyl-,(E);

Suppliers and Price of 1-(5-Chloro-2-hydroxy-phenyl)-3-phenyl-propenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-(5-Chloro-2-hydroxy-phenyl)-3-phenyl-propenone

Chemical Property:

PSA：37.30000
LogP:3.94170

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(5-Chloro-2-hydroxy-phenyl)-3-phenyl-propenone

There total 9 articles about 1-(5-Chloro-2-hydroxy-phenyl)-3-phenyl-propenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1450-74-4
5-chloro-2-hydroxyacetophenone

: 100-52-7
benzaldehyde

: 1218-24-2,52923-35-0
3-phenyl-1-(2'-hydroxy-5'-chlorophenyl)-2-propen-1-one

Guidance literature:: With sodium hydroxide; In ethanol; at 20 ℃;
DOI:10.1016/j.tetlet.2014.04.032

Reference yield: 87.9%

: 1450-74-4
5-chloro-2-hydroxyacetophenone

: 100-52-7
benzaldehyde

: 1218-24-2,52923-35-0
5'-chloro-2'-hydroxychalcone

Guidance literature:: 5-chloro-2-hydroxyacetophenone; With sodium hydroxide; In ethanol; water; at 0 ℃; for 0.5h;

benzaldehyde; In ethanol; water; at 0 - 20 ℃; for 12h;
DOI:10.1039/c3ob42429d

Reference yield: 43.0%

: 100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6
styrene

: 635-93-8
5-chlorosalicyclaldehyde

: 1218-24-2,52923-35-0
3-phenyl-1-(2'-hydroxy-5'-chlorophenyl)-2-propen-1-one

Guidance literature:: With 1,2,3,4-tetraphenylcyclopentadiene; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; copper diacetate; In 1,2-dichloro-ethane; at 120 ℃; for 18h; regioselective reaction; Inert atmosphere;
DOI:10.1002/anie.201203224