diMethyl 4,6-dihydroxyisophthalate

Base Information

• Chemical Name: diMethyl 4,6-dihydroxyisophthalate
• CAS No.: 52959-28-1
• Molecular Formula: C10H10O6
• Molecular Weight: 226.186
• Mol file: 52959-28-1.mol

Synonyms:dimethyl 4,6-dihydroxy-1,3-benzenedicarboxylate;4,6-Dihydroxy-isophthalic acid dimethyl ester;Dimethyl 2,4-dihydroxybenzene-1,5-dicarboxylate;4,6-Dihydroxy-isophthalsaeure-dimethylester;4,6-dihydroxy-isophtalic acid dimethyl ester;4,6-dihydroxyisophthalic acid dimethyl ester;

Chemical Property of diMethyl 4,6-dihydroxyisophthalate

Chemical Property:

• Melting Point: 146 - 148 °C
• PSA: 93.06000
• LogP: 0.67100

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diMethyl 4,6-dihydroxyisophthalate

There total 10 articles about diMethyl 4,6-dihydroxyisophthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

methanol (67-56-1) + 4,6-dihydroxyisophthalic acid (19829-74-4) → dimethyl 4,6-dihydroxyisophthalate (52959-28-1)

Guidance literature:

With sulfuric acid; for 60h; Reflux;

DOI:10.1039/c2cc16912f

Reference yield:

recorcinol (108-46-3) → dimethyl 4,6-dihydroxyisophthalate (52959-28-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 45 percent / 3 h / 210 °C

2: 90 percent / conc. H₂SO₄ / 48 h / Heating

With sulfuric acid; 1: Carboxylation / 2: Esterification;

DOI:10.1021/ja9942742

Reference yield:

recorcinol (108-46-3) → dimethyl 4,6-dihydroxyisophthalate (52959-28-1)

Guidance literature:

DOI:10.1016/0040-4039(94)85063-1

upstream raw materials:

diazomethane

4,6-dihydroxyisophthalic acid

methanol

dimethyl sulfate

Downstream raw materials:

2,6-dihydroxy-α-oxo-bibenzyl-3,5-dicarboxylic acid dimethyl ester

4,6-dimethoxyisophthalic acid dimethyl ester

2.5-Bis--terephthalsaeure-dimethylester

C₁₃H₁₇NO₅