Benzenesulfonamide, 4-methoxy-N-(phenylmethylene)-

Base Information

• Chemical Name: Benzenesulfonamide, 4-methoxy-N-(phenylmethylene)-
• CAS No.: 52960-60-8
• Molecular Formula: C14H13NO3S
• Molecular Weight: 275.328
• Mol file: 52960-60-8.mol

Synonyms:N-benzylidene-4-methoxy-benzenesulfonamide;4-methoxy-N-(phenylmethylene)benzenesulfonamide;Benzenesulfonamide,4-methoxy-N-(phenylmethylene);

Chemical Property of Benzenesulfonamide, 4-methoxy-N-(phenylmethylene)-

Chemical Property:

• Boiling Point: 439.2±47.0 °C(Predicted)
• PSA: 64.11000
• Density: 1.18±0.1 g/cm3(Predicted)
• LogP: 3.58380

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenesulfonamide, 4-methoxy-N-(phenylmethylene)-

There total 8 articles about Benzenesulfonamide, 4-methoxy-N-(phenylmethylene)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-methoxybenzene sulfonamide (1129-26-6) + benzaldehyde (100-52-7) → N-benzylidene-4-methoxy-benzenesulfonamide (52960-60-8)

Guidance literature:

With boron trifluoride diethyl etherate; In benzene; for 12h; Reflux;

DOI:10.1039/c5ob01140j

Reference yield: 81.0%

4-methoxybenzene sulfonamide (1129-26-6) + toluene (108-88-3,15644-74-3,16713-13-6) → N-benzylidene-4-methoxy-benzenesulfonamide (52960-60-8)

Guidance literature:

With oxygen; at 120 ℃; for 24h; under 7500.75 Torr; Autoclave;

DOI:10.1039/c2cc31438j

Reference yield: 78.0%

N-benzyl-4-methoxybenzenesulfonamide (119059-70-0) → N-benzylidene-4-methoxy-benzenesulfonamide (52960-60-8)

Guidance literature:

With N-hydroxyphthalimide; [bis(acetoxy)iodo]benzene; In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.3390/molecules24203771

upstream raw materials:

(diethoxymethyl)benzene

4-methoxybenzene sulfonamide

(2S,3S)-2-(4-Methoxy-benzenesulfonyl)-3-phenyl-oxaziridine

benzaldehyde dimethyl acetal

Downstream raw materials:

cis-2-(4-methoxy-benzenesulfonyl)-3-phenyl-oxaziridine

(2S,3S)-2-(4-Methoxy-benzenesulfonyl)-3-phenyl-oxaziridine

naphthalen-2-yl (S)-2-((4-Methoxyphenylsulfonamido)(phenylmethyl))acrylate

C₂₄H₂₄N₂O₅S