3-Methyl-1-phenyl-2-(1h) pyridone

Base Information

Chemical Name:3-Methyl-1-phenyl-2-(1h) pyridone
CAS No.:53427-93-3
Molecular Formula:C12H11NO
Molecular Weight:185.225
Hs Code.:
DSSTox Substance ID:DTXSID10431144
Nikkaji Number:J2.680.101J
Wikidata:Q82244954
Mol file:53427-93-3.mol

Synonyms:53427-93-3;3-methyl-1-phenyl-2-(1h) pyridone;2(1H)-Pyridinone, 3-methyl-1-phenyl-;3-methyl-1-phenylpyridin-2(1H)-one;3-methyl-1-phenylpyridin-2-one;SCHEMBL747392;DTXSID10431144;methyl-1-phenyl-2 (1h)-pyridone;1-Phenyl-3-methylpyridine-2(1H)-one

Suppliers and Price of 3-Methyl-1-phenyl-2-(1h) pyridone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 3-Methyl-1-phenyl-2-(1h) pyridone

Chemical Property:

PSA：22.00000
LogP:2.14590
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:185.084063974
Heavy Atom Count:14
Complexity:285

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CN(C1=O)C2=CC=CC=C2
Uses 3-Methyl-1-Phenyl-2(1H)-Pyridinone is an impurity in Pirfrnidone (CAS# 53179-13-8). May have anti-inflammatory properties.

Technology Process of 3-Methyl-1-phenyl-2-(1h) pyridone

There total 4 articles about 3-Methyl-1-phenyl-2-(1h) pyridone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 1003-56-1,91914-04-4
3-methylpyridin-2-ol

: 591-50-4
iodobenzene

: 53427-93-3
3-methyl-1-phenylpyridin-2(1H)-one

Guidance literature:: With copper(l) iodide; potassium carbonate; In N,N-dimethyl-formamide; at 150 ℃; for 16h; Inert atmosphere;
DOI:10.1039/c8cc04907f

Reference yield: 74.0%

: diphenyl(trifluoromethanesulfonato)-λ³-iodane

: 1003-56-1
3-Methyl-1H-pyridin-2-one

: 51933-79-0
3-methyl-2-phenoxypyridine

: 53427-93-3
3-methyl-1-phenylpyridin-2(1H)-one

Guidance literature:: With caesium carbonate; In 1,2-dichloro-ethane; at 120 ℃;
DOI:10.1055/s-0036-1591884

Reference yield:

: 1003-56-1
3-Methyl-1H-pyridin-2-one

: 591-50-4
iodobenzene

: 53427-93-3
3-methyl-1-phenylpyridin-2(1H)-one

Guidance literature:: With copper(l) iodide; potassium carbonate; In N,N-dimethyl-formamide; at 150 ℃; for 6h; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.orglett.7b01159