1-(Difluoromethyl)naphthalene

Base Information

Chemical Name:1-(Difluoromethyl)naphthalene
CAS No.:53731-26-3
Molecular Formula:C11H8F2
Molecular Weight:178.181
Hs Code.:
DSSTox Substance ID:DTXSID10456539
Nikkaji Number:J642.323J
Wikidata:Q82279085
Mol file:53731-26-3.mol

Synonyms:1-(difluoromethyl)naphthalene;53731-26-3;MFCD12546939;1-(diluoromethyl)naphthalene;SCHEMBL1538539;C11H8F2;DTXSID10456539;BVMYLIYGDBEEAX-UHFFFAOYSA-N;CHEBI:188691;AKOS005256340;SB85472;BS-52965;SY265659;CS-0453392;E84229

Suppliers and Price of 1-(Difluoromethyl)naphthalene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(Difluoromethyl)naphthalene 95+%
10g
$ 401.00

Chemenu
1-(Difluoromethyl)naphthalene 95%
10g
$ 379.00

American Custom Chemicals Corporation
1-(DIFLUOROMETHYL)NAPHTHALENE 95.00%
1G
$ 704.55

Total 7 raw suppliers

Chemical Property of 1-(Difluoromethyl)naphthalene

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:178.05940658
Heavy Atom Count:13
Complexity:168

Purity/Quality:

97% ^*data from raw suppliers

1-(Difluoromethyl)naphthalene 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CC=C2C(F)F

Technology Process of 1-(Difluoromethyl)naphthalene

There total 29 articles about 1-(Difluoromethyl)naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 75-45-6
Chlorodifluoromethane

: 13922-41-3
1-Naphthylboronic acid

: 53731-26-3
1-(difluoromethyl)naphthalene

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium carbonate; hydroquinone; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 110 ℃; for 48h; Inert atmosphere; Sealed tube;
DOI:10.1038/nchem.2746

Reference yield: 88.0%

: 90-11-9
1-Bromonaphthalene

: 65864-64-4
trimethyl(difluoromethyl)silane

: 53731-26-3
1-(difluoromethyl)naphthalene

Guidance literature:: With dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; cesium fluoride; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In 1,4-dioxane; at 100 ℃; for 16h; Reagent/catalyst; Glovebox; Sealed tube;
DOI:10.1021/acs.joc.9b00324