Chlorodifluoromethane

Base Information

• Chemical Name: Chlorodifluoromethane
• CAS No.: 75-45-6
• Deprecated CAS: 134191-96-1,191542-01-5,73666-77-0,191542-01-5,73666-77-0
• Molecular Formula: CHClF2
• Molecular Weight: 86.4687
• Hs Code.: 2903710000
• European Community (EC) Number: 200-871-9
• ICSC Number: 0049
• UN Number: 1018
• UNII: ZFO627O6CN
• DSSTox Substance ID: DTXSID6020301
• Nikkaji Number: J1.455I
• Wikipedia: Chlorodifluoromethane
• Wikidata: Q422994,Q83038270
• ChEMBL ID: CHEMBL116155
• Mol file: 75-45-6.mol

Synonyms:chlorodifluoromethane;fluorocarbon 22;Freon 22;Frigen;monochlorodifluoromethane

Chemical Property of Chlorodifluoromethane

Chemical Property:

• Appearance/Colour: Colourless gas
• Vapor Pressure: 6290mmHg at 25°C
• Melting Point: -146 °C
• Refractive Index: 1.278
• Boiling Point: -40.8 °C
• PSA: 0.00000
• Density: 1.277 g/cm³
• LogP: 1.44780
• Water Solubility.: Slightly soluble
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 85.9734841
• Heavy Atom Count: 4
• Complexity: 13.5
• Transport DOT Label: Non-Flammable Gas

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s): F
• Hazard Codes: 40-59
• Safety Statements: 23-59

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Chlorofluorocarbons
• Canonical SMILES: C(F)(F)Cl
• Inhalation Risk: On loss of containment this substance can cause suffocation by lowering the oxygen content of the air in confined areas.
• Effects of Short Term Exposure: Rapid evaporation of the liquid may cause frostbite. The substance may cause effects on the cardiovascular system and central nervous system. This may result in cardiac disorders and central nervous system depression. Exposure could cause lowering of consciousness.
• Uses: Refrigerant, low-temperature solvent, fluorocarbon resins, especially tetrafluoroethylene polymers. Aerosol propellant; refrigerant; lowtemperature solvent

Technology Process of Chlorodifluoromethane

There total 73 articles about Chlorodifluoromethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.4%

dichloromethane (75-09-2) + ammonia (7664-41-7) → hydrogen cyanide (74-90-8) + Methyl fluoride (593-53-3) + Difluoromethane (75-10-5) + Chlorodifluoromethane (75-45-6) + carbon dioxide (124-38-9,18923-20-1)

Guidance literature:

With catalyst: Pt/C; In neat (no solvent); steady-state flow reaction over Pt/C catalyst at 769 K;

DOI:10.1039/c39900001247

Reference yield: 24.0%

chlorodifluoroiodomethane (420-49-5) + potassium hydroxide → Chlorodifluoromethane (75-45-6) + potassium carbonate (584-08-7)

Guidance literature:

In ethanol; decompn. with alc. KOH at 35°C in 48h;;

Reference yield:

trifluoromethan (75-46-7) → Chlorodifluoromethane (75-45-6) + Dichlorofluoromethane (75-43-4) + chloroform (67-66-3,8013-54-5)

Guidance literature:

With dichloromethane; chlorine; at 250 ℃; for 0.00138889h; Concentration; Temperature; Reagent/catalyst;

upstream raw materials:

methane

Difluoromethane

dichloromethane

Dichlorofluoromethane

Downstream raw materials:

1,1,2-trichloro-3,3,3-trifluoropropene

1,2-di-tert-butoxy-1,2-difluoro-ethene

Diethyl difluoromethylphosphonate

difluoromethyl methyl ether

Refernces

• 1、 Simons. "". . p. 1308. Retrieved 1965.
• 2、 Majer et al.. "". . p. 122. Retrieved 1965.
• 3、 Leyland, L. M.,Majer, J. R.,Robb, J. C.. "". . p. 901 - 903. Retrieved 1970.
• 4、 -. "A trifluoro methane resource utilization method". Paragraph 0019; 0028-0063. . Retrieved 2017/08/25.
• 5、 Bonarowska, Magdalena,Raróg-Pilecka, Wioletta,Karpiński, Zbigniew. "The use of active carbon pretreated at 2173 K as a support for palladium catalysts for hydrodechlorination reactions". body text. p. 223 - 231. Retrieved 2012/02/03.