2,3-Dimethylbutanoic acid ethyl ester

Base Information

• Chemical Name: 2,3-Dimethylbutanoic acid ethyl ester
• CAS No.: 54004-42-1
• Molecular Formula: C8H16O2
• Molecular Weight: 144.214
• Hs Code.: 2915900090
• Mol file: 54004-42-1.mol

Synonyms:Butanoic acid, 2,3-dimethyl-, ethyl ester;Butanoic acid,2,3-dimethyl-,ethyl ester;Aethylester der (+-)-Methyl-isopropyl-essigsaeure;ethyl ester of/the/ (+-)-methyl-isopropyl-acetic acid;2,3-Dimethyl-buttersaeure-aethylester;2,3-dimethyl-butanoic acid,ethyl ester;

Chemical Property of 2,3-Dimethylbutanoic acid ethyl ester

Chemical Property:

• Boiling Point: 148-150 °C(Press: 745 Torr)
• PSA: 26.30000
• Density: 0.8719 g/cm3(Temp: 17.5 °C)
• LogP: 1.84160

Purity/Quality:

95% ^*data from raw suppliers

Ethyl2,3-Dimethylbutanoate 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-Dimethylbutanoic acid ethyl ester

There total 10 articles about 2,3-Dimethylbutanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

Ethyl isovalerate (108-64-5) + methyl iodide (74-88-4) → 2,3-dimethyl-butanoic acid, ethyl ester (54004-42-1)

Guidance literature:

Ethyl isovalerate; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere; Schlenk technique;

methyl iodide; In tetrahydrofuran; at -78 - 20 ℃; for 2h; Inert atmosphere; Schlenk technique;

DOI:10.1021/ja411772n

Reference yield: 84.0%

bromo-2 dimethyl-2,3 butyrate d'ethyle (122422-44-0) → 2,3-dimethyl-butanoic acid, ethyl ester (54004-42-1)

Guidance literature:

With water; lithium diisopropyl amide; In tetrahydrofuran; 1) -78 deg C, 30 min 2) 30 min;

Reference yield:

ethyl 2,3-dimethylbut-2-enoate (13979-28-7) → 2,3-dimethyl-butanoic acid, ethyl ester (54004-42-1)

Guidance literature:

With methanol; sodium tetrahydroborate; meso-tetraphenylporphyrin iron(III) chloride; In tetrahydrofuran; at 30 ℃; for 1h;

upstream raw materials:

ethanol

3-methylvaleric acid

Ethyl isovalerate

methyl iodide

Downstream raw materials:

(+/-)-2,3,4-trimethyl-2-pentanol

2,3-dimethylbutyric acid

2,3-dimethylbutanol

1-bromo-2,3-dimethyl-butane