4-Piperidineacetic acid, 1-benzoyl-, ethyl ester

Base Information

Chemical Name:4-Piperidineacetic acid, 1-benzoyl-, ethyl ester
CAS No.:54108-67-7
Molecular Formula:C16H21NO3
Molecular Weight:275.348
Hs Code.:
DSSTox Substance ID:DTXSID00438309
Wikidata:Q82254004

Synonyms:54108-67-7;4-Piperidineacetic acid, 1-benzoyl-, ethyl ester;ETHYL 2-(1-BENZOYLPIPERIDIN-4-YL)ACETATE;SCHEMBL8544211;DTXSID00438309;QTHLYHVTWAAQKP-UHFFFAOYSA-N;ethyl 1-benzoyl-4-piperidineacetate;N-benzoyl-4-(carbethoxymethyl)piperidine;D87450

Suppliers and Price of 4-Piperidineacetic acid, 1-benzoyl-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Piperidineacetic acid, 1-benzoyl-, ethyl ester

Chemical Property:

PSA：46.61000
LogP:2.42990
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:275.15214353
Heavy Atom Count:20
Complexity:329

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1CCN(CC1)C(=O)C2=CC=CC=C2

Technology Process of 4-Piperidineacetic acid, 1-benzoyl-, ethyl ester

There total 5 articles about 4-Piperidineacetic acid, 1-benzoyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.7%

: 21363-69-9
1-benzoyl-4-<(ethoxycarbonyl)methylene>piperidine

: 54108-67-7
N-benzoyl-4-(carbethoxymethyl)piperidine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 0.5h; under 760 Torr;
DOI:10.1021/jm00169a008

Reference yield:

: 59184-90-6
ethyl (piperidin-4-yl)acetate

: 98-88-4
benzoyl chloride

: 54108-67-7
N-benzoyl-4-(carbethoxymethyl)piperidine

Guidance literature:: With chloroform; water; potassium carbonate;
DOI:10.1021/ja01120a042

Reference yield:

: 24686-78-0
1-Benzoyl-4-piperidone

: 54108-67-7
N-benzoyl-4-(carbethoxymethyl)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / EtONa / ethanol / 1 h / 0 °C

2: 93.7 percent / H₂ / 10percent Pd/C / ethanol / 0.5 h / 760 Torr

With hydrogen; sodium ethanolate; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00169a008