1-Benzoyl-5-fluorouracil

Base Information

Chemical Name:1-Benzoyl-5-fluorouracil
CAS No.:54390-98-6
Molecular Formula:C11H7FN2O3
Molecular Weight:234.187
Hs Code.:2933599090
DSSTox Substance ID:DTXSID20541006
Nikkaji Number:J184.176I
Wikidata:Q63399362
Mol file:54390-98-6.mol

Synonyms:1-benzoyl-5-fluorouracil;54390-98-6;1-Benzoyl-5-fluoropyrimidine-2,4(1H,3H)-dione;SCHEMBL11098174;DTXSID20541006;RQNLYAYTZCUHLO-UHFFFAOYSA-N;Q63399362

Suppliers and Price of 1-Benzoyl-5-fluorouracil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-Benzoyl-5-fluorouracil

Chemical Property:

PSA：72.19000
LogP:0.77650
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:234.04407025
Heavy Atom Count:17
Complexity:400

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)N2C=C(C(=O)NC2=O)F

Technology Process of 1-Benzoyl-5-fluorouracil

There total 3 articles about 1-Benzoyl-5-fluorouracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 51-21-8
5-fluorouracil

: 98-88-4
benzoyl chloride

: 54390-98-6
N¹-Benzoyl-5-fluorouracil

Guidance literature:: With pyridine; In acetonitrile; for 1h;

Reference yield:

: triphosgene

: 1146220-98-5
N-[(1E)-2-carbamoyl-2-fluorovinyl]benzamide

: 54390-98-6
N¹-Benzoyl-5-fluorouracil

Guidance literature:: N-[(1E)-2-carbamoyl-2-fluorovinyl]benzamide; With sodium hydride; In 1,2-dimethoxyethane; at 20 ℃; for 3h;

triphosgene; In 1,2-dimethoxyethane; at 20 ℃; for 12h;
DOI:10.3987/COM-08-S(F)116