3-Pyridinecarboxylic acid, 2-[(phenylamino)thioxomethyl]hydrazide

Base Information

• Chemical Name: 3-Pyridinecarboxylic acid, 2-[(phenylamino)thioxomethyl]hydrazide
• CAS No.: 54584-49-5
• Molecular Formula: C13H12N4OS
• Molecular Weight: 272.33

Synonyms:1-nicotinoyl-4-phenyl thiosemicarbazide;1-nicotinoyl-4-phenyl-thiosemicarbazide;

Chemical Property of 3-Pyridinecarboxylic acid, 2-[(phenylamino)thioxomethyl]hydrazide

Chemical Property:

• PSA: 98.14000
• LogP: 2.56780

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pyridinecarboxylic acid, 2-[(phenylamino)thioxomethyl]hydrazide

There total 1 articles about 3-Pyridinecarboxylic acid, 2-[(phenylamino)thioxomethyl]hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

Nicotinic acid hydrazide (553-53-7) + phenyl isothiocyanate (103-72-0) → N-phenyl-2-(pyridin-3-ylcarbonyl)hydrazinecarbothioamide (54584-49-5)

Guidance literature:

In ethanol; for 0.5h; Heating;

DOI:10.1016/0223-5234(96)83976-6

Reference yield: 91.0%

oxalyl dichloride (79-37-8) + N-phenyl-2-(pyridin-3-ylcarbonyl)hydrazinecarbothioamide (54584-49-5) → N3-(4,5-dioxo-3-phenyl-2-thioxo-1-imidazolidinyl)nicotinamide (1048370-10-0)

Guidance literature:

In dichloromethane; at -20 - -10 ℃; for 1h;

DOI:10.3390/molecules13030501

Reference yield: 89.0%

N-phenyl-2-(pyridin-3-ylcarbonyl)hydrazinecarbothioamide (54584-49-5) → 4-phenyl-3-(pyridin-3-yl)-Δ2-1,2,4-triazoline-5-thione (57600-03-0)

Guidance literature:

With sodium hydroxide; In water; for 2h; Reflux;

DOI:10.3109/14756366.2013.855926

upstream raw materials:

Nicotinic acid hydrazide

phenyl isothiocyanate

Downstream raw materials:

N-phenyl-5-(pyridin-3-yl)-1,3,4-thiadiazol-2-amine

4-phenyl-3-(pyridin-3-yl)-Δ²-1,2,4-triazoline-5-thione

N-phenyl-5-(pyridin-3-yl)-1,3,4-oxadiazol-2-amine

N₃-(4,5-dioxo-3-phenyl-2-thioxo-1-imidazolidinyl)nicotinamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 54584-49-5 3-Pyridinecarboxylic acid, 2-[(phenylamino)thioxomethyl]hydrazide

Send

Send

Metric Ton KG G Pound L ML

Send

Send