2,2-Diphenyl-2H-1,3-benzodioxole-4-carboxylic acid

Base Information

Chemical Name:2,2-Diphenyl-2H-1,3-benzodioxole-4-carboxylic acid
CAS No.:54888-41-4
Molecular Formula:C20H14O4
Molecular Weight:318.329
Hs Code.:
DSSTox Substance ID:DTXSID30560001
Wikidata:Q82442940

Synonyms:54888-41-4;2,2-Diphenyl-2H-1,3-benzodioxole-4-carboxylic acid;SCHEMBL4860502;DTXSID30560001

Suppliers and Price of 2,2-Diphenyl-2H-1,3-benzodioxole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,2-Diphenyl-2H-1,3-benzodioxole-4-carboxylic acid

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:318.08920892
Heavy Atom Count:24
Complexity:433

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2(OC3=CC=CC(=C3O2)C(=O)O)C4=CC=CC=C4

Technology Process of 2,2-Diphenyl-2H-1,3-benzodioxole-4-carboxylic acid

There total 8 articles about 2,2-Diphenyl-2H-1,3-benzodioxole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 72553-33-4
methyl 2,2-diphenylbenzo[d][1,3]dioxole-4-carboxylate

: 54888-41-4
2,3-<(diphenylmethylene)dioxy>benzoic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; water; for 5h; Reflux;
DOI:10.1021/acs.inorgchem.6b02041

Reference yield:

: 303-38-8
2,3-Dihydroxybenzoic acid

: 54888-41-4
2,3-<(diphenylmethylene)dioxy>benzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: thionyl chloride / 78 °C / Inert atmosphere

2: triethylamine / 16 h / 0 - 25 °C / Inert atmosphere

3: neat (no solvent) / 160 °C / Inert atmosphere

4: potassium trimethylsilonate / tetrahydrofuran / 2 h / 70 °C / Inert atmosphere

With thionyl chloride; potassium trimethylsilonate; triethylamine; In tetrahydrofuran;
DOI:10.1039/c3ob41990h

Reference yield:

: 2411-83-8
methyl-2,3-dihydroxybenzoate

: 54888-41-4
2,3-<(diphenylmethylene)dioxy>benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: neat (no solvent) / 160 °C / Inert atmosphere

2: potassium trimethylsilonate / tetrahydrofuran / 2 h / 70 °C / Inert atmosphere

With potassium trimethylsilonate; In tetrahydrofuran;
DOI:10.1039/c3ob41990h