4-Octene-2,2,7,7-tetracarboxylic acid, 1,8-diphenyl-, tetraethyl ester, (E)-

Base Information

• Chemical Name: 4-Octene-2,2,7,7-tetracarboxylic acid, 1,8-diphenyl-, tetraethyl ester, (E)-
• CAS No.: 55053-90-2
• Molecular Formula: C₃₂H₄₀O₈
• Molecular Weight: 552.665
• Mol file: 55053-90-2.mol

Synonyms:

Chemical Property of 4-Octene-2,2,7,7-tetracarboxylic acid, 1,8-diphenyl-, tetraethyl ester, (E)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Octene-2,2,7,7-tetracarboxylic acid, 1,8-diphenyl-, tetraethyl ester, (E)-

There total 2 articles about 4-Octene-2,2,7,7-tetracarboxylic acid, 1,8-diphenyl-, tetraethyl ester, (E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

Natrium-benzylmalonsaeure-diaethylester (35472-53-8) + buta-1,3-diene (106-99-0,130983-70-9,29406-96-0,9003-17-2) → (E)-2,7-Dibenzyl-2,7-bis-ethoxycarbonyl-oct-4-enedioic acid diethyl ester (55053-90-2)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; ?-4-chlorobutenylpalladium; In tetrahydrofuran; 1) -30 deg C; 2) room temperature, 18 h;

DOI:10.1016/S0040-4039(01)82864-1

Reference yield:

1,4-dibromo-2-butene (6974-12-5) + diethyl 2-benzylmalonate (607-81-8) → (E)-2,7-Dibenzyl-2,7-bis-ethoxycarbonyl-oct-4-enedioic acid diethyl ester (55053-90-2)

Guidance literature:

Multistep reaction; (i) NaOEt, EtOH, (ii) /BRN= 1719694/;

upstream raw materials:

1,4-dibromo-2-butene

diethyl 2-benzylmalonate

Natrium-benzylmalonsaeure-diaethylester

buta-1,3-diene

Refernces