2-Benzyl-2-methyl-malonic acid diethyl ester

Base Information

Chemical Name:2-Benzyl-2-methyl-malonic acid diethyl ester
CAS No.:55114-30-2
Molecular Formula:C15H20O4
Molecular Weight:264.321
Hs Code.:
European Community (EC) Number:684-383-5
DSSTox Substance ID:DTXSID20391508
Nikkaji Number:J1.971.566C
Wikidata:Q82189007

Synonyms:55114-30-2;2-BENZYL-2-METHYL-MALONIC ACID DIETHYL ESTER;SCHEMBL8710582;Propanedioic acid, methyl(phenylmethyl)-, diethyl ester;DTXSID20391508;XVKFESUTLASBKM-UHFFFAOYSA-N;Diethyl 2-benzyl-2-methylmalonate;Benzylmethylmalonic acid diethyl ester;AKOS024322904

Suppliers and Price of 2-Benzyl-2-methyl-malonic acid diethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-Benzyl-2-methyl-malonic acid diethyl ester

Chemical Property:

PSA：52.60000
LogP:2.36160
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:264.13615911
Heavy Atom Count:19
Complexity:287

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C)(CC1=CC=CC=C1)C(=O)OCC

Technology Process of 2-Benzyl-2-methyl-malonic acid diethyl ester

There total 20 articles about 2-Benzyl-2-methyl-malonic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 607-81-8
diethyl 2-benzylmalonate

: 74-88-4
methyl iodide

: 55114-30-2
2-benzyl-2-methylmalonic acid diethyl ester

Guidance literature:: With potassium hydroxide; In N,N-dimethyl-formamide; at 0 - 14 ℃; for 3.33333h;
DOI:10.1016/j.tet.2009.02.076

Reference yield: 99.0%

: 1774-47-6
trimethylsulfoxonium iodide

: 607-81-8
diethyl 2-benzylmalonate

: 55114-30-2
2-benzyl-2-methylmalonic acid diethyl ester

Guidance literature:: diethyl 2-benzylmalonate; With sodium hydride; In tetrahydrofuran; mineral oil; at 25 ℃; for 0.5h; Sealed tube;

trimethylsulfoxonium iodide; In dimethyl sulfoxide; for 8h; Reagent/catalyst; Sealed tube; Reflux;
DOI:10.1021/acs.orglett.8b03641