3-(4-Methoxybenzylidene)-oxindole

Base Information

Chemical Name:3-(4-Methoxybenzylidene)-oxindole
CAS No.:55160-02-6
Molecular Formula:C16H13NO2
Molecular Weight:251.285
Hs Code.:
DSSTox Substance ID:DTXSID40384391
ChEMBL ID:CHEMBL5181621

Synonyms:3-(4-methoxybenzylidene)-oxindole;55160-02-6;3-(4-Methoxybenzylidene)-2-indolinone;3-[(4-methoxyphenyl)methylidene]-1H-indol-2-one;Maybridge3_000798;CHEMBL5181621;DTXSID40384391;SOHLANGNFXOOEF-UHFFFAOYSA-N;MFCD00118162;AKOS032455878;SY058405

Suppliers and Price of 3-(4-Methoxybenzylidene)-oxindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-(4-Methoxybenzylidene)-oxindole

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:251.094628657
Heavy Atom Count:19
Complexity:369

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C=C2C3=CC=CC=C3NC2=O

Technology Process of 3-(4-Methoxybenzylidene)-oxindole

There total 3 articles about 3-(4-Methoxybenzylidene)-oxindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 59-48-3
2-oxoindole

: 123-11-5
4-methoxy-benzaldehyde

: 55160-02-6
3-(4-methoxybenzylidene)indolin-2-one

Guidance literature:: With [1-(3-sulfonic acid)]propyl-3-methylimidazolium hydrogen sulfate; at 80 ℃; for 0.333333h;
DOI:10.1515/HC.2008.14.4.263

Reference yield:

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 55160-02-6
3-(4-methoxybenzylidene)indolin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrazine hydrate / 4 h / 140 °C

1.2: 48 h / 20 °C

2.1: piperidine / ethanol / 90 °C

With piperidine; hydrazine hydrate; In ethanol; 1.1: Wolff-Kishner reduction;
DOI:10.1248/cpb.59.1285