N-(2-chloro-4-hydroxyphenyl)acetamide

Base Information

Chemical Name:N-(2-chloro-4-hydroxyphenyl)acetamide
CAS No.:56074-07-8
Molecular Formula:C8H8ClNO2
Molecular Weight:185.61
Hs Code.:
DSSTox Substance ID:DTXSID00561949
Nikkaji Number:J29.364D
Wikidata:Q82445890
Mol file:56074-07-8.mol

Synonyms:4-acetamido-3-chlorophenol;N-(2-chloro-4-hydroxyphenyl)acetamide;56074-07-8;N-(2-Chloro-4-hydroxy-phenyl)-acetamide;SCHEMBL3323425;DTXSID00561949;CDGZSMOCDYNULJ-UHFFFAOYSA-N;AKOS014115210

Suppliers and Price of N-(2-chloro-4-hydroxyphenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemcia Scientific
N-(2-Chloro-4-hydroxy-phenyl)-acetamide 95%
5 G
$ 750.00

Total 4 raw suppliers

Chemical Property of N-(2-chloro-4-hydroxyphenyl)acetamide

Chemical Property:

PSA：52.82000
LogP:2.65350
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:185.0243562
Heavy Atom Count:12
Complexity:174

Purity/Quality:

95% ^*data from raw suppliers

N-(2-Chloro-4-hydroxy-phenyl)-acetamide 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=C(C=C(C=C1)O)Cl

Technology Process of N-(2-chloro-4-hydroxyphenyl)acetamide

There total 7 articles about N-(2-chloro-4-hydroxyphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 17609-80-2
4-amino-3-chlorophenol

: 56074-07-8
4-acetamido-3-chlorophenol

Guidance literature:: With sodium acetate; In acetic acid; for 12h; Heating / reflux;

Reference yield: 68.0%

: 17609-80-2
4-amino-3-chlorophenol

: 108-24-7
acetic anhydride

: 56074-07-8
4-acetamido-3-chlorophenol

Guidance literature:: 4-amino-3-chlorophenol; acetic anhydride; With triethylamine; In dichloromethane; at 0 - 20 ℃;

With methanol; potassium carbonate; at 0 ℃; for 1.5h;

With hydrogenchloride; water; In methanol; pH=3;

Reference yield: 55.0%

: 533-17-5
N-(2-chlorophenyl)acetamide

: 56074-07-8
4-acetamido-3-chlorophenol

Guidance literature:: With C₂₈H₄₆N₄O₁₀S₂; dihydrogen peroxide; acetic acid; iron(II) chloride; In water; acetonitrile; at 80 ℃; for 1h; regioselective reaction;
DOI:10.1126/science.abj0731