7-Benzyl-1H-Purine-2,6(3H,7H)-Dione

Base Information

• Chemical Name: 7-Benzyl-1H-Purine-2,6(3H,7H)-Dione
• CAS No.: 56160-64-6
• Molecular Formula: C12H10N4O2
• Molecular Weight: 242.237
• Mol file: 56160-64-6.mol

Synonyms:7-benzyl-3,7-dihydropurine-2,6-dione;7-benzylxanthine;7-Benzyl-3,7-dihydro-purin-2,6-dion;7-benzyl-xanthine;7-benzyl-3,7-dihydro-1H-purine-2,6-dione;7-benzyl-3,7-dihydro-purine-2,6-dione;

Chemical Property of 7-Benzyl-1H-Purine-2,6(3H,7H)-Dione

Chemical Property:

• PSA: 83.54000
• LogP: 0.46120

Purity/Quality:

97% ^*data from raw suppliers

7-Benzyl-1H-purine-2,6(3H,7H)-dione 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-Benzyl-1H-Purine-2,6(3H,7H)-Dione

There total 13 articles about 7-Benzyl-1H-Purine-2,6(3H,7H)-Dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.9%

2-amino-7-benzyl-1H-purin-6(7H)-one (17495-12-4) → 7-benzylxanthine (56160-64-6)

Guidance literature:

With water; acetic acid; sodium nitrite; at 20 - 50 ℃; for 2.5h;

Reference yield: 33.0%

urea (57-13-6) + ethyl 4-amino-1-benzyl-1H-imidazole-5-carboxylate (169616-29-9) → 7-benzylxanthine (56160-64-6)

Guidance literature:

urea; ethyl 4-amino-1-benzyl-1H-imidazole-5-carboxylate; In 2-methoxy-ethanol; at 190 ℃; for 24h;

With sodium hydroxide; In 2-methoxy-ethanol; water; for 3h; Heating;

DOI:10.1016/j.bmcl.2015.07.095

Reference yield:

2-amino-7-benzyl-1H-purin-6(7H)-one (17495-12-4) + sodium cyanide (773837-37-9) → 7-benzylxanthine (56160-64-6)

Guidance literature:

With acetic acid; In water; at 50 ℃; for 3h;

upstream raw materials:

2-amino-7-benzyl-1H-purin-6(7H)-one

benzyl bromide

guanosine

ethyl 2-(benzylamino)acetate

Downstream raw materials:

ethyl 7-benzylxanthine-3-acetate

diethyl 7-benzylxanthine-1,3-diacetate

2,2-Dimethylpropionic acid [7-benzyl-2,6-dioxo-1,2,6,7-tetrahydropurin-3-yl]methyl ester

(7-benzyl-3-[[(2,2-dimethylpropanoyl)oxy]methyl]-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl 2,2-dimethylpropanoate