Bis(3-methoxyphenoxy)methane

Base Information

• Chemical Name: Bis(3-methoxyphenoxy)methane
• CAS No.: 56207-33-1
• Molecular Formula: C15H16O4
• Molecular Weight: 260.29
• DSSTox Substance ID: DTXSID40449338
• Nikkaji Number: J1.912.560B
• Wikidata: Q82268764
• Mol file: 56207-33-1.mol

Synonyms:Bis(3-methoxyphenoxy)methane;56207-33-1;Benzene, 1,1'-[methylenebis(oxy)]bis[3-methoxy-;SCHEMBL11306471;DTXSID40449338;SY298192

Chemical Property of Bis(3-methoxyphenoxy)methane

Chemical Property:

• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 260.10485899
• Heavy Atom Count: 19
• Complexity: 222

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC(=CC=C1)OCOC2=CC=CC(=C2)OC

Technology Process of Bis(3-methoxyphenoxy)methane

There total 5 articles about Bis(3-methoxyphenoxy)methane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

O-methylresorcine (150-19-6) + dichloromethane (75-09-2) → formaldehyde-[bis-(3-methoxy-phenyl)-acetal] (56207-33-1)

Guidance literature:

O-methylresorcine; With sodium hydride; In 1-methyl-pyrrolidin-2-one;

dichloromethane; In 1-methyl-pyrrolidin-2-one; at 40 ℃; for 4h;

DOI:10.1081/SCC-120018936

Reference yield: 85.0%

dichloromethane (75-09-2) + sodium 3-methoxyphenolate (51113-99-6) → formaldehyde-[bis-(3-methoxy-phenyl)-acetal] (56207-33-1)

Guidance literature:

With 1-n-butyl-3-methylimidazolim bromide; at 60 ℃; for 1h;

DOI:10.1080/00397910500281267

Reference yield:

O-methylresorcine (150-19-6) + [1,3,5,7,2,6]tetroxadithiocane 2,2,6,6-tetraoxide (20757-83-9) → formaldehyde-[bis-(3-methoxy-phenyl)-acetal] (56207-33-1)

Guidance literature:

With sodium hydroxide; acetone; at 50 ℃;

DOI:10.1039/jr9310001765

upstream raw materials:

O-methylresorcine

[1,3,5,7,2,6]tetroxadithiocane 2,2,6,6-tetraoxide

diiodomethane

dichloromethane

Downstream raw materials:

C₁₅H₁₄I₂O₄