2-Methyl-2,3-dihydro-4H-1-benzopyran-4-one

Base Information

• Chemical Name: 2-Methyl-2,3-dihydro-4H-1-benzopyran-4-one
• CAS No.: 5631-75-4
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• Mol file: 5631-75-4.mol

Synonyms:2-Methyl-4-chromanone;2-methylchroman-4-one;2,3-dihydro-2-methylchromen-4-one;2,3-dihydro-2-methyl-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2,3-dihydro-2-methyl-;2-methylbenzindan-1-one;2-Methyldihydrochromanone;Methyl-2 chromanone-4;2-methyl-2,3-dihydrochromone;

Chemical Property of 2-Methyl-2,3-dihydro-4H-1-benzopyran-4-one

Chemical Property:

• PSA: 26.30000
• LogP: 2.04030

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Methyl-2,3-dihydro-4H-1-benzopyran-4-one

There total 5 articles about 2-Methyl-2,3-dihydro-4H-1-benzopyran-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

3-bromo-2-methylchroman-4-one → 2-methylchromone (5751-48-4) + 2,3-dihydro-2-methyl-4H-1-benzopyran-4-one (5631-75-4)

Guidance literature:

In acetonitrile; for 1h; Ambient temperature; Irradiation;

DOI:10.3987/com-95-7262

Reference yield: 60.0%

2-methylchromone (5751-48-4) → 2,3-dihydro-2-methyl-4H-1-benzopyran-4-one (5631-75-4)

Guidance literature:

With hydrogen; Lindlar's catalyst; In benzene; at 20 ℃; for 18h;

DOI:10.1016/S0968-0896(01)00207-3

Reference yield: 16.0%

but-3-enoic acid phenyl ester (46117-36-6) → 2,3-dihydro-2-methyl-4H-1-benzopyran-4-one (5631-75-4) + C10H10O2 (943454-93-1) + but-2-enoic acid phenyl ester (55673-53-5,46117-37-7) + phenol (108-95-2,27073-41-2)

Guidance literature:

With gold(III) chloride; In 1,2-dichloro-ethane; at 80 ℃; for 4h; Inert atmosphere;

DOI:10.1016/j.tetlet.2011.04.122

upstream raw materials:

2-methylchromone

1-(2-hydroxyphenyl)-3-phenyl-1,3-propanedione

ethanol

but-3-enoic acid phenyl ester

Downstream raw materials:

2,3-dihydro-2-methyl-4H-1-benzopyran-4-one 2,4-dinitrophenylhydrazone

2-methylchromone

2,3-dihydro-2-methyl-2-phenyl-4H-1-benzopyran-4-one