5-[(4-Fluoro-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine

Base Information

Chemical Name:5-[(4-Fluoro-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
CAS No.:56518-56-0
Molecular Formula:C13H15FN4O2
Molecular Weight:278.286
Hs Code.:
DSSTox Substance ID:DTXSID80496341
Wikidata:Q82345130

Synonyms:56518-56-0;5-[(4-Fluoro-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine;SCHEMBL11595225;DTXSID80496341

Suppliers and Price of 5-[(4-Fluoro-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-[(4-Fluoro-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:278.11790390
Heavy Atom Count:20
Complexity:296

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1F)OC)CC2=CN=C(N=C2N)N

Technology Process of 5-[(4-Fluoro-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine

There total 2 articles about 5-[(4-Fluoro-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3,5-dimethoxy-4-phenylazo-benzoic acid methyl ester

: 67-71-0
dimethylsulfone

: 56066-25-2
methyl 3,5-dimethoxy-4-aminobenzoate

: 56066-27-4
4-amino-3,5-dimethoxy-α-[(methylsulfonyl)-methyl]-benzyl alcohol

: 56518-56-0
5-(4-fluoro-3,5-dimethoxy-benzyl)-pyrimidine-2,4-diamine

Guidance literature:: With sodium borohydrid; hydrogen; palladium on charcoal; In ethanol; water; dimethyl sulfoxide;

Reference yield:

: 56518-56-0
5-(4-fluoro-3,5-dimethoxy-benzyl)-pyrimidine-2,4-diamine

Guidance literature:: 4-Fluor-3,5-dimethoxy-benzaldehyd, 1) 3-Morpholino-propionitril, NaOMe in DMSO, 65-70grad, 2) Anilin, konz.HCl, iPrOH, Δ, 3) Guanidin-hydrochlorid, NaOMe in A., Δ;
DOI:10.1002/hlca.19770600854