1-(4-fluorobenzyl)-1H-imidazole

Base Information

Chemical Name:1-(4-fluorobenzyl)-1H-imidazole
CAS No.:56643-73-3
Molecular Formula:C10H9FN2
Molecular Weight:176.193
Hs Code.:
UNII:7J8LU26YRA
ChEMBL ID:CHEMBL377770
DSSTox Substance ID:DTXSID90481445
Pharos Ligand ID:AKY8DFKYZKP5
Wikidata:Q82316871

Synonyms:1-(4-fluorobenzyl)-1H-imidazole;56643-73-3;1-(4-Fluorobenzyl)imidazole;7J8LU26YRA;CHEMBL377770;1-((4-Fluorophenyl)methyl)imidazole;1-((4-Fluorophenyl)methyl)-1H-imidazole;1-[(4-FLUOROPHENYL)METHYL]IMIDAZOLE;1H-Imidazole, 1-((4-fluorophenyl)methyl)-;UNII-7J8LU26YRA;CHEMBL-377770;SCHEMBL11082155;DTXSID90481445;BDBM50188085;AKOS003644474;PD178990

Suppliers and Price of 1-(4-fluorobenzyl)-1H-imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(4-Fluorobenzyl)-1H-imidazole 97%
5g
$ 1131.00

Crysdot
1-(4-Fluorobenzyl)-1H-imidazole 97%
1g
$ 437.00

Total 3 raw suppliers

Chemical Property of 1-(4-fluorobenzyl)-1H-imidazole

Chemical Property:

PSA：17.82000
LogP:2.07050
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:176.07497646
Heavy Atom Count:13
Complexity:155

Purity/Quality:

99% ^*data from raw suppliers

1-(4-Fluorobenzyl)-1H-imidazole 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CN2C=CN=C2)F

Technology Process of 1-(4-fluorobenzyl)-1H-imidazole

There total 4 articles about 1-(4-fluorobenzyl)-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 288-32-4
1H-imidazole

: 459-46-1
4-Fluorobenzyl bromide

: 56643-73-3
1-(4-fluorobenzyl)-1H-imidazole

Guidance literature:: 1H-imidazole; With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 2h;

4-Fluorobenzyl bromide; In dimethyl sulfoxide; at 20 ℃; for 3h;
DOI:10.1021/jacs.7b03131

Reference yield: 76.0%

: 456-41-7
1-(Bromomethyl)-3-fluorobenzene

: 459-46-1
4-Fluorobenzyl bromide

: 56643-73-3
1-(4-fluorobenzyl)-1H-imidazole

Guidance literature:: In acetonitrile; at 60 ℃; for 4h;
DOI:10.1016/S0040-4020(97)00487-0

Reference yield:

: 288-32-4
1H-imidazole

: 352-11-4
1-chloromethyl-4-fluorobenzene

: 56643-73-3
1-(4-fluorobenzyl)-1H-imidazole

Guidance literature:: 1H-imidazole; With potassium carbonate; In N,N-dimethyl-formamide; for 0.333333h;

1-chloromethyl-4-fluorobenzene; In N,N-dimethyl-formamide; at 50 ℃; for 2h;
DOI:10.1016/j.ejmech.2012.05.039