N-[3,5-bis(trifluoromethyl)phenyl]-4-chlorobenzamide

Base Information

Chemical Name:N-[3,5-bis(trifluoromethyl)phenyl]-4-chlorobenzamide
CAS No.:56661-30-4
Molecular Formula:C15H8ClF6NO
Molecular Weight:367.678
Hs Code.:
DSSTox Substance ID:DTXSID90384407
Wikidata:Q82176527

Synonyms:N-[3,5-bis(trifluoromethyl)phenyl]-4-chlorobenzamide;HMS549A17;56661-30-4;CDS1_000369;Maybridge1_002657;ST51014332;DivK1c_001409;SCHEMBL11799771;DTXSID90384407;BZLNVIUAFGKMPS-UHFFFAOYSA-N;CCG-35107;STK330024;AKOS005438921

Suppliers and Price of N-[3,5-bis(trifluoromethyl)phenyl]-4-chlorobenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-[3,5-bis(trifluoromethyl)phenyl]-4-chlorobenzamide

Chemical Property:

XLogP3:6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:367.0198605
Heavy Atom Count:24
Complexity:422

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)Cl

Technology Process of N-[3,5-bis(trifluoromethyl)phenyl]-4-chlorobenzamide

There total 2 articles about N-[3,5-bis(trifluoromethyl)phenyl]-4-chlorobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 637-87-6
1-Chloro-4-iodobenzene

: 201230-82-2
carbon monoxide

: 328-74-5
3,5-Bis-(trifluoromethyl)aniline

: 56661-30-4
N-(3,5-bis(trifluoromethyl)phenyl) 4-chlorobenzamide

Guidance literature:: With palladium diacetate; triethylamine; triphenylphosphine; In toluene; at 80 ℃; for 17h; Sealed tube;
DOI:10.1002/chem.202002746

Reference yield:

: 56661-30-4
N-(3,5-bis(trifluoromethyl)phenyl) 4-chlorobenzamide

Guidance literature:: 3,5-Di(trifluormethyl)-anilin, p-Cl-benzoylchlorid;

Reference yield:

: 111-34-2,92680-80-3
-butyl vinyl ether

: 56661-30-4
N-(3,5-bis(trifluoromethyl)phenyl) 4-chlorobenzamide

: (R)-N-(3,5-bis(trifluoromethyl)phenyl)-2-(1-butoxyethyl)-4-chlorobenzamide

: N-(3,5-bis(trifluoromethyl)phenyl)-2,6-bis(1-butoxyethyl)-4-chlorobenzamide

: C₂₁H₂₀ClF₆NO₂

Guidance literature:: With [(1,5-cyclooctadiene)(OH)iridium(I)]2; 5-[(3aR,8aR)-tetrahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-5H-dibenzo[b,f]azepine; In toluene; at 80 ℃; for 20h; enantioselective reaction; Schlenk technique; Inert atmosphere;
DOI:10.1055/a-1672-6284