Tetrahydropyranyl ether

Base Information

• Chemical Name: Tetrahydropyranyl ether
• CAS No.: 709-84-2
• Molecular Formula: C10H18 O3
• Molecular Weight: 186.251
• NSC Number: 97549
• DSSTox Substance ID: DTXSID60294645
• Nikkaji Number: J3.353.293H
• Mol file: 709-84-2.mol

Synonyms:tetrahydropyranyl ether;709-84-2;NSC97549;ditetrahydropyranyl ether;bis(tetrahyropyranyl)ether;di-tetrahydropyranyl ether;monotetrahydropyranyl ether;bis(tetrahydropyranyl)ether;bis-tetrahydropyranyl ether;tetrahydropyran-2-yl ether;mono-tetrahydropyranyl ether;SCHEMBL30805;bistetrahydropyran-2-yl ether;SCHEMBL10926551;DTXSID60294645;(tetrahydro-2H-pyran-2-yl)ether;HUHXLHLWASNVDB-UHFFFAOYSA-N;NSC-97549;FT-0719110

Chemical Property of Tetrahydropyranyl ether

Chemical Property:

• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 186.125594432
• Heavy Atom Count: 13
• Complexity: 133

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCOC(C1)OC2CCCCO2

Technology Process of Tetrahydropyranyl ether

There total 5 articles about Tetrahydropyranyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(tert-butylperoxy)tetrahydro-2H-pyran (28627-46-5) → 2-methoxytetrahydropyran (6581-66-4) + 3,4,5,6-tetrahydro-2H-pyran-2-one (542-28-9,26354-94-9) + bis-tetrahydropyran-2-yl ether (709-84-2) + acetone (67-64-1)

Guidance literature:

at 250 ℃;

DOI:10.1021/ja01638a012

Reference yield:

3,4-dihydro-2H-pyran (110-87-2) → tetrahydro-2H-2-pyranol (694-54-2) + bis-tetrahydropyran-2-yl ether (709-84-2) + 5-hydroxypentanal (4221-03-8)

Guidance literature:

With hydrogenchloride; Yield given. Yields of byproduct given; 1.) 25 deg C, 1 h, 2.) reflux, 24 h;

Reference yield:

3,4-dihydro-2H-pyran (110-87-2) → tetrahydro-2H-2-pyranol (694-54-2) + bis-tetrahydropyran-2-yl ether (709-84-2) + 5-(2-tetrahydropyranyloxy)pentanal (14194-86-6) + 5-hydroxypentanal (4221-03-8)

Guidance literature:

With hydrogenchloride; for 0.25h; Product distribution; Ambient temperature; other times and temperatures, other hydration reagent;

upstream raw materials:

3,4-dihydro-2H-pyran

2-(tert-butylperoxy)tetrahydro-2H-pyran

Downstream raw materials:

1 ,5-pentanediol

lithium cyclohexylisopropylamide

tetrahydro-2H-2-pyranol

dimethyl (3-phenoxy-2-oxopropyl)phosphonate

Refernces

• 1、 Vinczer, Peter,Juvancz, Zoltan,Novak, Lajos,Szantay, Csaba. "REINVESTIGATION OF THE HYDRATION OF 3,4-DIHYDRO-2H-PYRAN". . p. 581 - 585. Retrieved 2007/10/02.