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2-METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE-3-CARBOXYLIC METHYL ESTER-1,1-DIOXIDE

Base Information Edit
  • Chemical Name:2-METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE-3-CARBOXYLIC METHYL ESTER-1,1-DIOXIDE
  • CAS No.:35511-15-0
  • Molecular Formula:C11H11NO5S
  • Molecular Weight:269.278
  • Hs Code.:2934991000
  • Mol file:35511-15-0.mol
2-METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE-3-CARBOXYLIC METHYL ESTER-1,1-DIOXIDE

Synonyms:2-Methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylicacid methyl ester 1,1-dioxide;4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid methyl ester1,1-dioxide;

Suppliers and Price of 2-METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE-3-CARBOXYLIC METHYL ESTER-1,1-DIOXIDE
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Methyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide
  • 250mg
  • $ 322.00
  • TRC
  • Methyl4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate1,1-Dioxide
  • 500mg
  • $ 105.00
  • Medical Isotopes, Inc.
  • Methyl-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate1,1-Dioxide
  • 500 mg
  • $ 875.00
  • Medical Isotopes, Inc.
  • Methyl4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate1,1-Dioxide(PiroxicamImpurityJ)
  • 10 g
  • $ 775.00
  • Matrix Scientific
  • Methyl 2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide 95+%
  • 1g
  • $ 231.00
  • Matrix Scientific
  • Methyl 2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide 95+%
  • 5g
  • $ 599.00
  • Crysdot
  • Methyl2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate1,1-dioxide 97%
  • 25g
  • $ 305.00
  • Chemenu
  • Methyl2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate1,1-dioxide 97%
  • 25g
  • $ 294.00
  • Biosynth Carbosynth
  • Methyl 4-hydroxy-2-methyl-(2H)-1,2-benzothiazine-3-carboxylate-1,1-dioxide
  • 5 g
  • $ 75.00
  • Biosynth Carbosynth
  • Methyl 4-hydroxy-2-methyl-(2H)-1,2-benzothiazine-3-carboxylate-1,1-dioxide
  • 25 g
  • $ 225.00
Total 76 raw suppliers
Chemical Property of 2-METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE-3-CARBOXYLIC METHYL ESTER-1,1-DIOXIDE Edit
Chemical Property:
  • Appearance/Colour:Off-white to pale yellow solid 
  • Vapor Pressure:0mmHg at 25°C 
  • Melting Point:163-165 °C 
  • Refractive Index:1.632 
  • Boiling Point:439.9 °C at 760 mmHg 
  • PKA:4.50±1.00(Predicted) 
  • Flash Point:219.8 °C 
  • PSA:92.29000 
  • Density:1.515 g/cm3 
  • LogP:1.73900 
  • Storage Temp.:-20?C Freezer 
  • Solubility.:Chloroform (Slightly), Methanol (Slightly) 
Purity/Quality:

99% *data from raw suppliers

Methyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Uses Piroxicam Impurity J. It Is also an impurity found in Meloxicam (M216100). Methyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide (Piroxicam EP Impurity J) is an impurity found in Meloxicam (M216100).
Technology Process of 2-METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE-3-CARBOXYLIC METHYL ESTER-1,1-DIOXIDE

There total 19 articles about 2-METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE-3-CARBOXYLIC METHYL ESTER-1,1-DIOXIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With potassium hydroxide; N-butylpyridinium tetrafluoroborate; at 40 ℃; for 6h;
DOI:10.1248/cpb.54.1175
Guidance literature:
methyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide; With sodium hydroxide; In water; acetone; at 20 ℃; for 0.0833333h;
dimethyl sulfate; In water; acetone; for 0.583333h;
With hydrogenchloride; In water; acetone;
DOI:10.1016/j.ejmech.2011.03.020
Guidance literature:
With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 5.5h;
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