[S-(E)]-3,7,11-trimethyldodeca-1,6,10-trien-3-ol

Base Information

• Chemical Name: [S-(E)]-3,7,11-trimethyldodeca-1,6,10-trien-3-ol
• CAS No.: 1119-38-6
• Molecular Formula: C15H26 O
• Molecular Weight: 222.371
• Mol file: 1119-38-6.mol

Synonyms:1,6,10-Dodecatrien-3-ol,3,7,11-trimethyl-, (E)-(S)-(+)- (8CI); 1,6,10-Dodecatrien-3-ol,3,7,11-trimethyl-, [S-(E)]-; (+)-trans-Nerolidol; (3S)-(E)-Nerolidol;(3S)-trans-Nerolidol; (S)-(+)-trans-Nerolidol; (S)-trans-Nerolidol;trans-(+)-Nerolidol

Chemical Property of [S-(E)]-3,7,11-trimethyldodeca-1,6,10-trien-3-ol

Chemical Property:

• Vapor Pressure: 0.000616mmHg at 25°C
• Boiling Point: 276°Cat760mmHg
• PKA: 14.40±0.29(Predicted)
• Flash Point: 109.9°C
• PSA: 20.23000
• Density: 0.869g/cm³
• LogP: 4.39630

Purity/Quality:

98%,99%, ^*data from raw suppliers

trans-(S)-Nerolidol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: trans-(S)-Nerolidol is an antifeeding sesquiterpene alcohol for gypsy moth larvae. An isoprene-related compound.

Technology Process of [S-(E)]-3,7,11-trimethyldodeca-1,6,10-trien-3-ol

There total 20 articles about [S-(E)]-3,7,11-trimethyldodeca-1,6,10-trien-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(2R,3R)-epoxyfarnesyl iodide (85431-78-3) → (S)-(+)-nerolidol (1119-38-6)

Guidance literature:

With florisil; acetic acid; zinc; In diethyl ether;

DOI:10.1016/S0040-4020(01)87533-5

Reference yield: 97.0%

(2S,3S)-2-((E)-4,8-Dimethyl-nona-3,7-dienyl)-3-iodomethyl-2-methyl-oxirane (85431-78-3) → (R)-(-)-trans-nerolidol (142-50-7,1119-38-6,2211-29-2,3790-78-1,7212-44-4,17430-12-5,35944-21-9,40716-66-3,53991-23-4,77171-59-6,132958-73-7,77551-75-8)

Guidance literature:

With zinc; In diethyl ether; acetic acid; for 1h; Ambient temperature;

DOI:10.1016/0040-4039(82)80144-5

Reference yield: 92.0%

(2R,3R)-epoxyfarnesyl tosylate (147127-73-9) → (S)-(+)-nerolidol (1119-38-6)

Guidance literature:

With sodium hydroxide; tellurium; sodium formaldehyde sulfoxylate; In tetrahydrofuran; Ambient temperature;

DOI:10.1021/jo00055a029

upstream raw materials:

9-phenylsulfonyl nerolidol

(2S,3S)-2-((E)-4,8-Dimethyl-nona-3,7-dienyl)-3-iodomethyl-2-methyl-oxirane

Farnesol

Toluene-4-sulfonic acid (2R,3S)-3-((E)-4,8-dimethyl-nona-3,7-dienyl)-3-methyl-oxiranylmethyl ester

Downstream raw materials:

(+)-3β-bromo-8-epicaparrapi oxide

(3aR)-(+)-sclareolide

Farnesal

(2Z,6E)-farnesal