Benzenemethanamine, a-(dimethoxymethyl)-

Base Information

• Chemical Name: Benzenemethanamine, a-(dimethoxymethyl)-
• CAS No.: 57962-58-0
• Molecular Formula: C10H15NO2
• Molecular Weight: 181.235
• Mol file: 57962-58-0.mol

Synonyms:2,2-dimethoxy-1-phenyl-ethylamine;1-phenyl-2,2-dimethoxyethylamine;2,2-dimethoxy-1-phenylethanamine;amino-phenyl-acetaldehyde dimethylacetal;(+-)-2,2-Dimethoxy-1-phenyl-aethylamin;Amino-phenyl-acetaldehyd-dimethylacetal;

Chemical Property of Benzenemethanamine, a-(dimethoxymethyl)-

Chemical Property:

• Boiling Point: 118 °C (5 mmHg)
• PSA: 44.48000
• LogP: 2.00560

Purity/Quality:

99% ^*data from raw suppliers

2,2-dimethoxy-1-phenylethan-1-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenemethanamine, a-(dimethoxymethyl)-

There total 6 articles about Benzenemethanamine, a-(dimethoxymethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N,N-dibenzyl-2,2-dimethoxy-1-phenylethanamine (1402067-59-7) → rac-2,2-dimethoxy-1-phenylethanamine (57962-58-0)

Guidance literature:

With 20% Pd/C; hydrogen; In methanol; at 20 ℃; for 24h;

DOI:10.1002/anie.201204215

Reference yield: 90.0%

N-allyl-N-(2,2-dimethoxy-1-phenylethyl)prop-2-en-1-amine (1402067-68-8) → rac-2,2-dimethoxy-1-phenylethanamine (57962-58-0)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; 1,3-dimethylbarbituric acid; In dichloromethane; at 20 ℃;

DOI:10.1002/anie.201204215

Reference yield:

benzylamino-phenyl-acetaldehyde dimethylacetal (101582-03-0) → rac-2,2-dimethoxy-1-phenylethanamine (57962-58-0)

Guidance literature:

With hydrogen; 5% Pd(II)/C(eggshell); In methanol; at 55 - 70 ℃; for 17h; under 15001.5 Torr;

upstream raw materials:

benzylamino-phenyl-acetaldehyde dimethylacetal

benzylamine

N,N-dibenzyl-2,2-dimethoxy-1-phenylethanamine

N-allyl-N-(2,2-dimethoxy-1-phenylethyl)prop-2-en-1-amine

Downstream raw materials:

(R)-2,2-dimethoxy-1-phenylethanamine

(S)-1-phenyl-2,2-dimethoxyethylamine

C₁₆H₁₅NO₃

(+/-)-benzyl 2-hydroxy-1-phenylethylcarbamate