Diethyl {[4-(dimethylamino)phenyl]methyl}propanedioate

Base Information

Chemical Name:Diethyl {[4-(dimethylamino)phenyl]methyl}propanedioate
CAS No.:58353-47-2
Molecular Formula:C16H23NO4
Molecular Weight:293.35800
Hs Code.:
DSSTox Substance ID:DTXSID40505362
Nikkaji Number:J1.759.973I
Wikidata:Q82360418

Synonyms:58353-47-2;Diethyl {[4-(dimethylamino)phenyl]methyl}propanedioate;DTXSID40505362

Suppliers and Price of Diethyl {[4-(dimethylamino)phenyl]methyl}propanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Diethyl {[4-(dimethylamino)phenyl]methyl}propanedioate

Chemical Property:

Boiling Point:169-170 °C(Press: 0.2 Torr)
PSA：55.84000
Density:1.100±0.06 g/cm3(Predicted)
LogP:2.03750
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:293.16270821
Heavy Atom Count:21
Complexity:317

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C(CC1=CC=C(C=C1)N(C)C)C(=O)OCC

Technology Process of Diethyl {[4-(dimethylamino)phenyl]methyl}propanedioate

There total 5 articles about Diethyl {[4-(dimethylamino)phenyl]methyl}propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3435-56-1
diethyl p-(N,N'-dimethylamino)-benzylidenemalonate

: 58353-47-2
2-(4-Dimethylamino-benzyl)-malonic acid diethyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; under 760 Torr; Yield given; Ambient temperature;
DOI:10.1248/cpb.31.560

Reference yield:

: 105-53-3
diethyl malonate

: 58353-47-2
2-(4-Dimethylamino-benzyl)-malonic acid diethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 234 g / piperidine / toluene / 10 h / Heating

2: H₂ / 5percent Pd/C / tetrahydrofuran / Ambient temperature

With piperidine; hydrogen; palladium on activated charcoal; In tetrahydrofuran; toluene;
DOI:10.1021/jm00081a024

Reference yield:

: 100-10-7
4-dimethylamino-benzaldehyde

: 58353-47-2
2-(4-Dimethylamino-benzyl)-malonic acid diethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 234 g / piperidine / toluene / 10 h / Heating

2: H₂ / 5percent Pd/C / tetrahydrofuran / Ambient temperature

With piperidine; hydrogen; palladium on activated charcoal; In tetrahydrofuran; toluene;
DOI:10.1021/jm00081a024