1,5-Hexanediol, 2-ethyl-

Base Information

Chemical Name:1,5-Hexanediol, 2-ethyl-
CAS No.:58374-34-8
Molecular Formula:C8H18O2
Molecular Weight:146.23
Hs Code.:
DSSTox Substance ID:DTXSID40476346

Synonyms:1,5-Hexanediol, 2-ethyl-;2-ethylhexane-1,5-diol;58374-34-8;2-ethyl-hexane-1,5-diol;SCHEMBL427001;DTXSID40476346;AKOS006327066;AS-77713;D97248

Suppliers and Price of 1,5-Hexanediol, 2-ethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 15 raw suppliers

Chemical Property of 1,5-Hexanediol, 2-ethyl-

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:146.130679813
Heavy Atom Count:10
Complexity:73.7

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC(CCC(C)O)CO

Technology Process of 1,5-Hexanediol, 2-ethyl-

There total 1 articles about 1,5-Hexanediol, 2-ethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 35650-55-6,553638-75-8
2-ethyl-5-oxo-hexanal

: 58374-34-8
2-ethyl-hexane-1,5-diol

Guidance literature:: With sodium tetrahydroborate; In ethanol; at 20 ℃; for 2h;
DOI:10.1007/s007060200084

Reference yield: 68.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 58374-34-8
2-ethyl-hexane-1,5-diol

: 1027426-93-2
1-(tert-butyldimethylsilyloxy)-2-ethyl-hexane-5-ol

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 3h;
DOI:10.1007/s007060200084

Reference yield:

: 58374-34-8
2-ethyl-hexane-1,5-diol

: 40321-98-0
mono(2-ethyl-5-oxohexyl) 1,2-benzenedicarboxylate

Guidance literature:: Multi-step reaction with 6 steps

1: 68 percent / imidazole / dimethylformamide / 3 h / 20 °C

2: 88 percent / imidazole; 4-dimethylaminopyridine / CH₂Cl₂ / 17 h / 20 °C

3: 76 percent / pyridinium p-toluenesulfonate / ethanol / 66 h / 20 °C

4: 86 percent / pyridine / 72 h / 20 °C

5: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 72 h / 20 °C

6: 56 percent / oxalyl chloride; DMSO; Et₃N / CH₂Cl₂ / 0.5 h / -65 °C

With 1H-imidazole; dmap; oxalyl dichloride; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; pyridine; ethanol; dichloromethane; N,N-dimethyl-formamide; 6: Swern oxidation;
DOI:10.1007/s007060200084