1-ACETAMIDO-4-BROMONAPHTHALENE

Base Information

• Chemical Name: 1-ACETAMIDO-4-BROMONAPHTHALENE
• CAS No.: 91394-66-0
• Molecular Formula: C12H10BrNO
• Molecular Weight: 264.121
• Hs Code.: 2924299090
• Mol file: 91394-66-0.mol

Synonyms:Acetamide,N-(4-bromo-1-naphthyl)- (6CI,7CI);4-Bromo-1-acetamidonaphthalene;N-(4-Bromo-1-naphthyl)acetamide;NSC 38943;

Chemical Property of 1-ACETAMIDO-4-BROMONAPHTHALENE

Chemical Property:

• Vapor Pressure: 1.92E-08mmHg at 25°C
• Melting Point: 160-163°C
• Refractive Index: 1.69
• Boiling Point: 454.3 °C at 760 mmHg
• Flash Point: 228.6 °C
• PSA: 29.10000
• Density: 1.528 g/cm³
• LogP: 3.63370
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

N-(4-Bromonaphthalen-1-yl)acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-ACETAMIDO-4-BROMONAPHTHALENE

There total 14 articles about 1-ACETAMIDO-4-BROMONAPHTHALENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.8%

4-Bromo-1-naphthylamine (2298-07-9) + acetic anhydride (108-24-7) → 1-(acetylamino)-4-bromonaphthalene (91394-66-0)

Guidance literature:

In methanol; at 0 ℃; for 1h; Reflux;

DOI:10.1124/mol.113.087502

Reference yield: 95.0%

1-acetamidonaphthalene (575-36-0) → 1-(acetylamino)-4-bromonaphthalene (91394-66-0)

Guidance literature:

With hexamethylene tetramine hydrobromide perbromide; In methanol; dichloromethane; at 25 - 28 ℃; for 0.75h;

DOI:10.1080/00397919308009839

Reference yield: 75.0%

4-Bromo-1-naphthylamine (2298-07-9) + acetic acid (64-19-7,77671-22-8) → 1-(acetylamino)-4-bromonaphthalene (91394-66-0)

Guidance literature:

In methanol; at 70 ℃; for 2h;

upstream raw materials:

methanol

N-(4,6,7-tribromo-5,6,7,8-tetrahydro-[1]naphthyl)-acetamide

1,3-dibromo-5,5-dimethyl-hydantoin

chloroform

Downstream raw materials:

2-(4-iodonaphthalen-2-ylamino)-5-nitrobenzoic acid