Propanedioic acid, [(3,5-dimethoxyphenyl)methyl]-, diethyl ester

Base Information

Chemical Name:Propanedioic acid, [(3,5-dimethoxyphenyl)methyl]-, diethyl ester
CAS No.:5859-68-7
Molecular Formula:C16H22O6
Molecular Weight:310.347
Hs Code.:
DSSTox Substance ID:DTXSID40445870
Nikkaji Number:J2.723.562J
Wikidata:Q82264411

Synonyms:Propanedioic acid, [(3,5-dimethoxyphenyl)methyl]-, diethyl ester;5859-68-7;SCHEMBL490334;DTXSID40445870;diethyl 2-(3,5-dimethoxybenzyl)malonate;2-(3,5-Dimethoxybenzyl)malonic acid diethyl ester

Suppliers and Price of Propanedioic acid, [(3,5-dimethoxyphenyl)methyl]-, diethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Propanedioic acid, [(3,5-dimethoxyphenyl)methyl]-, diethyl ester

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:10
Exact Mass:310.14163842
Heavy Atom Count:22
Complexity:327

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(CC1=CC(=CC(=C1)OC)OC)C(=O)OCC

Technology Process of Propanedioic acid, [(3,5-dimethoxyphenyl)methyl]-, diethyl ester

There total 8 articles about Propanedioic acid, [(3,5-dimethoxyphenyl)methyl]-, diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 5859-67-6
diethyl 2-(3,5-dimethoxybenzylidene)malonate

: 5859-68-7
[(3,5-dimethoxyphenyl)methyl]propanedioic acid diethyl ester

Guidance literature:: With sodium tetrahydroborate; In ethanol; for 0.25h; Cooling with ice;
DOI:10.1016/j.tet.2009.03.057

Reference yield: 77.0%

: 877-88-3
3,5-dimethoxybenzyl bromide

: 105-53-3
diethyl malonate

: 5859-68-7
[(3,5-dimethoxyphenyl)methyl]propanedioic acid diethyl ester

Guidance literature:: With caesium carbonate; In acetonitrile; at 130 ℃; for 0.166667h; Sealed tube; Irradiation;
DOI:10.21577/0103-5053.20180202

Reference yield:

: 705-76-0
3,5-dimethoxybenzyl alcohol

: 5859-68-7
[(3,5-dimethoxyphenyl)methyl]propanedioic acid diethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: phosphorus tribromide / 1,4-dioxane / 1 h / 40 °C / Inert atmosphere

2: caesium carbonate / acetonitrile / 0.17 h / 130 °C / Sealed tube; Irradiation

With phosphorus tribromide; caesium carbonate; In 1,4-dioxane; acetonitrile;
DOI:10.21577/0103-5053.20180202