2-(Pyrrolidin-1-yl)nicotinonitrile

Base Information

Chemical Name:2-(Pyrrolidin-1-yl)nicotinonitrile
CAS No.:59025-38-6
Molecular Formula:C10H11N3
Molecular Weight:173.217
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50424696
Wikidata:Q82237371
Mol file:59025-38-6.mol

Synonyms:2-(Pyrrolidin-1-yl)nicotinonitrile;59025-38-6;3-Cyano-2-pyrrolidinopyridine;2-(pyrrolidin-1-yl)pyridine-3-carbonitrile;2-pyrrolidin-1-ylnicotinonitrile;2-pyrrolidin-1-ylpyridine-3-carbonitrile;2-Pyrrolidin-1-yl-nicotinonitrile;SCHEMBL565864;DTXSID50424696;BHRCNCKRRFUYAS-UHFFFAOYSA-N;BBL030866;MFCD07792921;STL199437;AKOS000190965;AS-8129;SB53055;CS-0453979;EN300-55216;F84185;A869299

Suppliers and Price of 2-(Pyrrolidin-1-yl)nicotinonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Cyano-2-pyrrolidinopyridine
1g
$ 75.00

TRC
3-Cyano-2-pyrrolidinopyridine
500mg
$ 65.00

TRC
3-Cyano-2-pyrrolidinopyridine
100mg
$ 45.00

SynQuest Laboratories
2-Pyrrolidin-1-ylnicotinonitrile
10 g
$ 621.00

SynQuest Laboratories
2-Pyrrolidin-1-ylnicotinonitrile
5 g
$ 373.00

SynQuest Laboratories
2-Pyrrolidin-1-ylnicotinonitrile
1 g
$ 125.00

Matrix Scientific
2-Pyrrolidin-1-ylnicotinonitrile
500mg
$ 237.00

Crysdot
2-(Pyrrolidin-1-yl)nicotinonitrile 95+%
25g
$ 677.00

Crysdot
2-(Pyrrolidin-1-yl)nicotinonitrile 95+%
10g
$ 384.00

Chemenu
2-Pyrrolidin-1-ylnicotinonitrile 95%
10g
$ 363.00

Total 10 raw suppliers

Chemical Property of 2-(Pyrrolidin-1-yl)nicotinonitrile

Chemical Property:

Boiling Point:338.8±27.0 °C(Predicted)
PKA:3.61±0.29(Predicted)
PSA：39.92000
Density:1.18±0.1 g/cm3(Predicted)
LogP:1.61848
Storage Temp.:Room temperature.
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:173.095297364
Heavy Atom Count:13
Complexity:212

Purity/Quality:

99%, ^*data from raw suppliers

3-Cyano-2-pyrrolidinopyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)C2=C(C=CC=N2)C#N

Technology Process of 2-(Pyrrolidin-1-yl)nicotinonitrile

There total 4 articles about 2-(Pyrrolidin-1-yl)nicotinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 123-75-1
pyrrolidine

: 3939-13-7
3-cyano-2-fluoropyridine

: 59025-38-6
2-(pyrrolidin-1-yl)nicotinonitrile

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 0.5h;

Reference yield: 74.0%

: 123-75-1
pyrrolidine

: 20577-26-8
2-bromonicotinonitrile

: 59025-38-6
2-(pyrrolidin-1-yl)nicotinonitrile

Guidance literature:: With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); N,N,N′,N′-tetramethyl-N″-tert-butylguanidine; 4-phenyl-N-methylpyridinium iodide; 4,4'-di-tert-butyl-2,2'-bipyridine; zinc; In dimethyl sulfoxide; at 80 ℃; for 8h; Reagent/catalyst; Inert atmosphere;
DOI:10.1002/chem.202002800